PXD009541

PXD009541 is an original dataset announced via ProteomeXchange.

Title	CTDP1 BRCT domain PPI - CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI
Description	The BRCT domain is commonly found in DNA damage response proteins, but its role in the phosphatase CTDP1 is unknown. This project examined the protein-protein interactions (PPI) associated with the CTDP1 BRCT domain region only and identified 106 significant interacting partners. Many of these partners play prominent roles in distinct DNA damage repair pathways and reveal novel functions of CTDP1 in these pathways.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:44:36.791.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD009541
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Nicholas Woods
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	Phospho; Oxidation; Carbamidomethyl
Instrument	LTQ Orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2018-04-19 02:31:40	ID requested
1	2019-06-04 02:43:12	announced
2	2019-07-12 02:58:12	announced	Updated publication reference for PubMed record(s): 31240132.
⏵ 3	2024-10-22 04:44:45	announced	2024-10-22: Updated project metadata.

Hu WF, Krieger KL, Lagund, ž, in D, Li X, Cheung RS, Taniguchi T, Johnson KR, Bessho T, Monteiro ANA, Woods NT, CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI. Cell Death Discov, 5():105(2019) [pubmed]

10.6019/PXD009541;

10.1038/s41420-019-0185-3;

curator keyword: Biological

submitter keyword: BRCT DNA Damage LC-MSMS

Nicholas T. Woods, Ph.D.
contact affiliation	Molecular & Biochemical Etiology Program Eppley Institute for Research in Cancer Fred & Pamela Buffett Cancer Center University of Nebraska Medical Center USA
contact email	nicholas.woods@unmc.edu
lab head
Nicholas Woods
contact affiliation	University of Nebraska Medical Center - Eppley Institute for Research in Cancer
contact email	nicholas.woods@unmc.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/06/PXD009541

PRIDE project URI

• PRIDE
  1. PXD009541
     1. Label: PRIDE project
     2. Name: CTDP1 BRCT domain PPI - CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI