PXD009463

PXD009463 is an original dataset announced via ProteomeXchange.

Title	Resuscitation from the viable but nonculturable state of Escherichia coli: the importance of a pyruvate sensing network
Description	Viable but nonculturable (VBNC) organisms have been underestimated and neglected when studying dormant phenotypes. In clinical settings, VBNC cells may contribute to non-apparent infections capable of being reactivated after months or even years, as for the case of Mycobacterium tuberculosis. The lack of specific and reliable methodology prevents the proper characterization of the VBNC state. Ultimately, these organisms pose a public health risk with potential implications in several industries ranging from pharmaceuticals to food industry. Research regarding their induction and resuscitation is of major importance. Bacteria are able to respond to several environmental and physiological oscillations in part via two-component systems (TCSs). BtsS/BtsR and YpdA/YpdB are two TCSs of Escherichia coli that form a pyruvate sensing network. Their role in the VBNC state is explored in this study.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:44:22.955.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ignasi Forne
SpeciesList	scientific name: Escherichia coli; NCBI TaxID: 562;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2018-04-11 00:27:41	ID requested
1	2018-11-23 04:07:06	announced
⏵ 2	2024-10-22 04:44:31	announced	2024-10-22: Updated project metadata.

10.1128/jb.00610-18;

Vilhena C, Kaganovitch E, Gr, ü, nberger A, Motz M, Forn, é I, Kohlheyer D, Jung K, K-12. J Bacteriol, 201(3):(2019) [pubmed]

curator keyword: Biological

submitter keyword: heterogeneity,metabolism, oxidative stress, scavenging

Prof. Dr. Kirsten Jung
contact affiliation	Ludwig-Maximilians Universität München Biozentrum Department Biologie I, Ber. Mikrobiologie Großhaderner Str. 2-4 82152 Martinsried
contact email	jung@lmu.de
lab head
Ignasi Forne
contact affiliation	Biomedical Center-LMU
contact email	ignasi.forne@lrz.uni-muenchen.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/11/PXD009463

PRIDE project URI

• PRIDE
  1. PXD009463
     1. Label: PRIDE project
     2. Name: Resuscitation from the viable but nonculturable state of Escherichia coli: the importance of a pyruvate sensing network