PXD009424

PXD009424 is an original dataset announced via ProteomeXchange.

Title	Fibroblasts grown in 3D - Three-Dimensional Cell Culture Conditions Affect the Proteome of Cancer-Associated Fibroblasts
Description	Here, we introduce a 3D cell culture system based on a mixture of collagen I and matrigelTM amenable to stable isotope labeling by amino acids in cell culture and quantitative mass spectrometry-based proteomics analyses. We study the extra- and intracellular proteomic response of skin fibroblast isolated from healthy volunteers in comparison to cancer-associated fibroblasts (CAFs) on 3D culture conditions
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:44:28.424.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Joern Dengjel
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116; scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2018-04-06 02:56:40	ID requested
1	2018-09-10 07:55:02	announced
⏵ 2	2024-10-22 04:44:36	announced	2024-10-22: Updated project metadata.

10.1021/acs.jproteome.8b00237;

T, ö, lle RC, Gaggioli C, Dengjel J, Three-Dimensional Cell Culture Conditions Affect the Proteome of Cancer-Associated Fibroblasts. J Proteome Res, 17(8):2780-2789(2018) [pubmed]

curator keyword: Biomedical

submitter keyword: cancer, skin, LC-MS,human, fibroblasts

Joern Dengjel
contact affiliation	Department of Biology, University of Fribourg, Chemin du Musée 10, 1700 Fribourg, Switzerland
contact email	joern.dengjel@unifr.ch
lab head
Joern Dengjel
contact affiliation	University of Fribourg
contact email	joern.dengjel@medizin.uni-freiburg.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/09/PXD009424

PRIDE project URI

• PRIDE
  1. PXD009424
     1. Label: PRIDE project
     2. Name: Fibroblasts grown in 3D - Three-Dimensional Cell Culture Conditions Affect the Proteome of Cancer-Associated Fibroblasts