PXD009399

PXD009399 is an original dataset announced via ProteomeXchange.

Title	TMT-based quantitative proteomics of plasma from chicken challenged with lipopolysaccharide endotoxin
Description	The change in the plasma proteome in chicken (Gallus gallus) challenged with lipopolysaccharide (endotoxin) derived from E. coli was determined by relative quantitation using a TMT label-based approach. This study provides insights into different factors contributing to innate immune response to experimental infection during 72 hours with special emphasis on acute phase proteins (APPs). Apart from APPs, several pathways endopeptidase activation and vasoconstriction were found to be significant.
HostingRepository	PRIDE
AnnounceDate	2018-08-20
AnnouncementXML	Submission_2018-08-20_02:55:19.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Anita Horvatic
SpeciesList	scientific name: Gallus gallus (Chicken); NCBI TaxID: 9031;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2018-04-04 08:31:17	ID requested
⏵ 1	2018-08-20 02:55:21	announced

Horvati, ć A, Guillemin N, Kaab H, McKeegan D, O'Reilly E, Bain M, Kule, š J, Eckersall PD, Quantitative proteomics using tandem mass tags in relation to the acute phase protein response in chicken challenged with Escherichia coli lipopolysaccharide endotoxin. J Proteomics, 192():64-77(2019) [pubmed]

curator keyword: Biological

submitter keyword: Chicken, lipopolysaccharide endotoxin infection, plasma, quantitative proteomics, TMT

David Eckersall
contact affiliation	ERA Chair laboratory, Internal Diseases Clinic, Faculty of Veterinary Medicine, University of Zagreb, Croatia
contact email	David.Eckersall@glasgow.ac.uk
lab head
Anita Horvatic
contact affiliation	University of Zagreb, Faculty of Veterinary Medicine
contact email	horvatic.ani@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/08/PXD009399

PRIDE project URI

• PRIDE
  1. PXD009399
     1. Label: PRIDE project
     2. Name: TMT-based quantitative proteomics of plasma from chicken challenged with lipopolysaccharide endotoxin