PXD009394 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Characterization of a nonhuman primate model for the study of testicular peritubular cells – comparison with human testicular cells |
Description | Smooth-muscle-like peritubular cells make up the wall of semniferous tubules of men. These human testicular peritubular cells (HTPC) have been shown to fulfill different roles. They transport sperm, secrete various factors like GDNF (glial cell line derived neurotrophic factor) and are immunologically active. They might contribute to spermatogonial stem cell niche altering and testicular ageing. Previous studies were limited regarding heterogeneity (due to lifestyle, age, medical history etc.) and accessibility of HTPCs. To circumvent this problem a cellular primate model should be established. The proteome of 6 MKTPCs of individual healthy and young (2 or 3 years) donors was assessed to investigate the suitability as a model. |
HostingRepository | PRIDE |
AnnounceDate | 2018-06-06 |
AnnouncementXML | Submission_2018-06-06_06:29:00.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Jan Bernd Stöckl |
SpeciesList | scientific name: Callithrix jacchus; NCBI TaxID: 9483; |
ModificationList | iodoacetamide derivatized residue |
Instrument | TripleTOF 5600 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2018-04-04 04:12:03 | ID requested | |
⏵ 1 | 2018-06-06 06:29:01 | announced | |
Publication List
Schmid N, St, ö, ckl JB, Flenkenthaler F, Dietrich KG, Schwarzer JU, K, ö, hn FM, Drummer C, Fr, ö, hlich T, Arnold GJ, Behr R, Mayerhofer A, Characterization of a non-human primate model for the study of testicular peritubular cells-comparison with human testicular peritubular cells. Mol Hum Reprod, 24(8):401-410(2018) [pubmed] |
Keyword List
curator keyword: Biological |
submitter keyword: proteome, testis, marmoset monkey, DDA, MaxQuant, HTPC, MKTPC, peritubular testicular cells |
Contact List
Georg J. Arnold |
contact affiliation | Laboratory for Functional Genome Analysis LAFUGA, Gene Center, LMU München, Fedor-Lynen-Strasse 25, 81377 Munich, Germany |
contact email | arnold@genzentrum.lmu.de |
lab head | |
Jan Bernd Stöckl |
contact affiliation | Genzentrum der LMU München |
contact email | stoeckl@genzentrum.lmu.de |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD009394
- Label: PRIDE project
- Name: Characterization of a nonhuman primate model for the study of testicular peritubular cells – comparison with human testicular cells