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PXD009279

PXD009279 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic analysis of E. coli K-12 LE392, P. putida KT2440 under exposure of carbamazepine
DescriptionThe goals of this study are to use SWATH-MS to detect bacterial proteomic profiles of wild-type E. coli K-12 LE392, P. putida KT2440, and their quantitative protein response under the exposure of antiepileptic drug carbamazepine. Three concentrations of carbamazepine were applied, which were 0.05 mg/L, 10.0 mg/L and 50.0 mg/L. The group without dosing carbamazepine was the control group. Each concentration was conducted in triplicate. By comparing the proteomic profiles of experimental groups and control group, the effects of carbamazepine on bacterial translational levels can be revealed.
HostingRepositoryPRIDE
AnnounceDate2018-10-11
AnnouncementXMLSubmission_2018-10-11_00:30:18.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJianhua Guo
SpeciesList scientific name: Escherichia coli; NCBI TaxID: 562; scientific name: Pseudomonas putida KT2440; NCBI TaxID: 160488;
ModificationListNo PTMs are included in the dataset
InstrumentTripleTOF 5600
Dataset History
RevisionDatetimeStatusChangeLog Entry
02018-03-21 05:09:06ID requested
12018-10-10 08:03:33announced
22018-10-11 00:30:19announcedUpdated project metadata.
Publication List
Wang Y, Lu J, Mao L, Li J, Yuan Z, Bond PL, Guo J, Antiepileptic drug carbamazepine promotes horizontal transfer of plasmid-borne multi-antibiotic resistance genes within and across bacterial genera. ISME J, 13(2):509-522(2019) [pubmed]
Keyword List
curator keyword: Biomedical
submitter keyword: E. coli, P. putida, carbamazepine, SWATH-MS
Contact List
Jianhua Guo
contact affiliationAdvanced Water Management Centre, The University of Queensland, St. Lucia, Brisbane, Queensland, Australia, 4072
contact emailj.guo@awmc.uq.edu.au
lab head
Jianhua Guo
contact affiliationUniversity of Queensland
contact emailj.guo@awmc.uq.edu.au
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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