PXD009266 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | A549 overexpressing CCAR1 LC-MS/MS |
Description | CCAR1 mRNA have two transcripts, the 3.5 kb full length transcript and the 2.5 kb shorter transcript which contained a deletion in exon 15—exon 22 of full-length CCAR1 cDNA, where sequences mapped to 1196–3120 bp were missed. CCAR1L and CCAR1S shared a common N-terminus and a common C-terminal end, but the latter had a deletion of SAP domain. As a DNA/RNA-binding domain, the SAP motif is involved in chromosomal organization and apoptosis. To explaine the divergence of CCAR1L and CCAR1S in regulating apoptosis,we purified CCAR1L and CCAR1S from flag-CCAR1L or CCAR1S overexpressing A549 cells by performing IP-MS to screening the possible proteins which are specifically interacting with CCAR1L or CCAR1S. |
HostingRepository | PRIDE |
AnnounceDate | 2018-05-15 |
AnnouncementXML | Submission_2018-06-28_23:40:41.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Huang Qingyang |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2018-03-20 08:35:47 | ID requested | |
1 | 2018-05-15 08:15:29 | announced | |
⏵ 2 | 2018-06-28 23:40:42 | announced | Updated publication reference for PubMed record(s): 29942010. |
Publication List
Chen Y, Huang Q, Liu W, Zhu Q, Cui CP, Xu L, Guo X, Wang P, Liu J, Dong G, Wei W, Liu CH, Feng Z, He F, Zhang L, Mutually exclusive acetylation and ubiquitylation of the splicing factor SRSF5 control tumor growth. Nat Commun, 9(1):2464(2018) [pubmed] |
Keyword List
curator keyword: Biological |
submitter keyword: A549,CCAR1,IP-MS |
Contact List
Zhang Lingqiang |
contact affiliation | State Key Laboratory of Proteomics, Beijing Proteome Research Center, |
contact email | zhanglq@nic.bmi.ac.cn |
lab head | |
Huang Qingyang |
contact affiliation | State Key Laboratory of Proteomics, Beijing Proteome Research Center, Beijing Institute of Radiation Medicine, National Center for Protein Sciences (The PHOENIX Center, Beijing), Beijing 102206, China. |
contact email | qingyang89@hotmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD009266
- Label: PRIDE project
- Name: A549 overexpressing CCAR1 LC-MS/MS