PXD009194

PXD009194 is an original dataset announced via ProteomeXchange.

Title	Label-free quantitative Proteomics Analysis Reveals Distinct Molecular characteristics in Endocardial Endothelium
Description	Endocardial endothelium, which lines the chambers of the heart, is distinct in its origin, structure, and function. However, though functionally very important, no studies at protein level have been conducted so far characterizing endocardial endothelium. In this study, we used endothelial cells from pig heart to investigate if endocardial endothelial cells are distinct at the proteome level. Using a high throughput liquid chromatography-tandem mass spectrometry for proteome profiling and expression, we identified sets of proteins that belong to specific biological processes and metabolic pathways in endocardial endothelial cells supporting its specific structural and functional roles.
HostingRepository	PRIDE
AnnounceDate	2018-06-29
AnnouncementXML	Submission_2018-06-29_09:20:39.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD009194
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Aneesh Kumar
SpeciesList	scientific name: Sus scrofa domesticus (domestic pig); NCBI TaxID: 9825;
ModificationList	Ammonia-loss; Dehydrated; Oxidation; Carbamidomethyl
Instrument	Synapt MS

Revision	Datetime	Status	ChangeLog Entry
0	2018-03-13 04:57:07	ID requested
⏵ 1	2018-06-29 09:20:40	announced

Jaleel A, Aneesh Kumar A, Ajith Kumar GS, Surendran A, Kartha CC, Label-free quantitative proteomics analysis reveals distinct molecular characteristics in endocardial endothelium. Mol Cell Biochem, 451(1-2):1-10(2019) [pubmed]

submitter keyword: Endothelium, Endocardium, Aorta, Label free proteomics

Dr Abdul Jaleel KA
contact affiliation	Scientist F, Diabetes Biology Laboratory
contact email	jaleel@rgcb.res.in
lab head
Aneesh Kumar
contact affiliation	PhD Student
contact email	aneeshkumar@rgcb.res.in
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD009194
     1. Label: PRIDE project
     2. Name: Label-free quantitative Proteomics Analysis Reveals Distinct Molecular characteristics in Endocardial Endothelium