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DataSet Summary

  • HostingRepository: PRIDE
  • AnnounceDate: 2019-03-14
  • AnnouncementXML: Submission_2019-03-14_03:04:54.xml
  • DigitalObjectIdentifier:
  • ReviewLevel: Peer-reviewed dataset
  • DatasetOrigin: Original data
  • RepositorySupport: Unsupported dataset by repository
  • PrimarySubmitter: Moo-Jin Suh
  • Title: Klebsiella pneumoniae protomic response to antibiotics
  • Description: Bacteria can circumvent the effect of antibiotics by transitioning to a poorly understood physiological state that does not involve conventional genetic elements of resistance. Here we examine antibiotic susceptibility with a Class A β-lactamase+ invasive strain of Klebsiella pneumoniae that was isolated from a lethal outbreak within laboratory colonies of Chlorocebus aethiops sabaeus monkeys. Bacterial responses to the ribosomal synthesis inhibitors streptomycin and doxycycline resulted in distinct proteomic adjustments that facilitated decreased susceptibility to each antibiotic.
  • SpeciesList: scientific name: Klebsiella pneumoniae; NCBI TaxID: 573;
  • ModificationList: iodoacetamide derivatized residue
  • Instrument: Orbitrap Fusion

Dataset History

VersionDatetimeStatusChangeLog Entry
02018-03-12 02:00:20ID requested
12019-03-14 03:04:56announced

Publication List

  1. Keasey SL, Suh MJ, Das S, Blancett CD, Zeng X, Andresson T, Sun MG, Ulrich RG, Proteome. Mol Cell Proteomics, 18(4):657-668(2019) [pubmed]

Keyword List

  1. curator keyword: Biomedical
  2. submitter keyword: Klebsiella pneumoniae, LC-MS/MS, Doxycycline, Streptomycin

Contact List

    Moojin Suh
    • contact affiliation: U.S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA
    • contact email: Jinisuh@gmail.com
    • lab head:
    Moo-Jin Suh
    • contact affiliation: USAMRIID
    • contact email: jinisuh@gmail.com
    • dataset submitter:

Full Dataset Link List

  1. Dataset FTP location
  2. PRIDE project URI
Repository Record List

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