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PXD009154

DataSet Summary

  • HostingRepository: PRIDE
  • AnnounceDate: 2018-08-09
  • AnnouncementXML: Submission_2018-08-09_09:22:30.xml
  • DigitalObjectIdentifier:
  • ReviewLevel: Peer-reviewed dataset
  • DatasetOrigin: Original data
  • RepositorySupport: Unsupported dataset by repository
  • PrimarySubmitter: Alister Craig
  • Title: Differential BN analysis of cytoadherence complexes in P. falciparum
  • Description: The pathogenesis of severe malaria has been associated with the ability of P. falciparum infected erythrocyte binding to host endothelium (a process known as cytoadherence) but the mechanisms underlying this have not been clearly described. To understand more about the molecular components that allow the parasite to modulate the behaviour of host endothelium and interact with endothelial molecules, we have used a combined proteomic technique of protein separation (1D Blue-Native electrophoresis) and mass spectrometry to study the interaction of infected erythrocytes (IE) with endothelial cells (EC) in a co-culture system.
  • SpeciesList: scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
  • ModificationList: monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
  • Instrument: LTQ

Dataset History

VersionDatetimeStatusChangeLog Entry
02018-03-09 03:32:05ID requested
12018-08-09 09:22:30announced

Publication List

  1. Dataset with its publication pending

Keyword List

  1. ProteomeXchange project tag: Malaria Host-Pathogen Interaction Center (MaHPIC)
  2. curator keyword: Biological
  3. submitter keyword: human, endothelium, plasmodium, malaria

Contact List

    Alister Craig
    • contact affiliation: Liverpool School of Tropical Medicine
    • contact email: alister.craig@lstmed.ac.uk
    • lab head:
    Alister Craig
    • contact affiliation: Liverpool School of Tropical Medicine
    • contact email: alister.craig@lstmed.ac.uk
    • dataset submitter:

Full Dataset Link List

  1. Dataset FTP location
  2. PRIDE project URI
Repository Record List
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