PXD009154

PXD009154 is an original dataset announced via ProteomeXchange.

Title	Differential BN analysis of cytoadherence complexes in P. falciparum
Description	The pathogenesis of severe malaria has been associated with the ability of P. falciparum infected erythrocyte binding to host endothelium (a process known as cytoadherence) but the mechanisms underlying this have not been clearly described. To understand more about the molecular components that allow the parasite to modulate the behaviour of host endothelium and interact with endothelial molecules, we have used a combined proteomic technique of protein separation (1D Blue-Native electrophoresis) and mass spectrometry to study the interaction of infected erythrocytes (IE) with endothelial cells (EC) in a co-culture system.
HostingRepository	PRIDE
AnnounceDate	2018-08-09
AnnouncementXML	Submission_2018-08-09_09:22:30.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Alister Craig
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	LTQ

Revision	Datetime	Status	ChangeLog Entry
0	2018-03-09 03:32:05	ID requested
⏵ 1	2018-08-09 09:22:30	announced

Dataset with its publication pending

ProteomeXchange project tag: Malaria Host-Pathogen Interaction Center (MaHPIC)

curator keyword: Biological

submitter keyword: human, endothelium, plasmodium, malaria

Alister Craig
contact affiliation	Liverpool School of Tropical Medicine
contact email	alister.craig@lstmed.ac.uk
lab head
Alister Craig
contact affiliation	Liverpool School of Tropical Medicine
contact email	alister.craig@lstmed.ac.uk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/08/PXD009154

PRIDE project URI

• PRIDE
  1. PXD009154
     1. Label: PRIDE project
     2. Name: Differential BN analysis of cytoadherence complexes in P. falciparum