PXD009135 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Identification of adsorbing human plasma proteins on alginate gel beads |
Description | The biocompatibility of immunoisolation devices is a major challenge for their use in cellular therapies. Utilisation of alginate for the encapsulation of pancreatic islets as a potential cellular therapy for type 1 diabetes has shown to be limited in terms of long-term graft survival, due to pericapsular fibrotic overgrowth. Fibrotic overgrowth is a complex process that involves several factors, including protein adsorption. This work investigates the protein adsorption profiles of plasma incubated alginate beads for the identification of key proteins that may play a role in the biocompatibility of this biomaterial. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_07:43:33.402.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Animesh Sharma |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | deamidated residue |
Instrument | LTQ Orbitrap Elite |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2018-03-08 01:27:14 | ID requested | |
1 | 2023-03-10 12:58:24 | announced | |
⏵ 2 | 2023-11-14 07:43:38 | announced | 2023-11-14: Updated project metadata. |
Publication List
Coron AE, Fonseca DM, Sharma A, Slupphaug G, Strand BL, Rokstad AMA, MS-proteomics provides insight into the host responses towards alginate microspheres. Mater Today Bio, 17():100490(2022) [pubmed] |
Keyword List
curator keyword: Technical, Biomedical |
submitter keyword: Alginate gel beads, biocompatibility, protein adsorption, proteomics |
Contact List
Geir Slupphaug |
contact affiliation | Professor i molekylærbiologi og faglig leder av PROMEC Institutt for klinisk og molekylær medisin Fakultet for medisin og helsevitenskap geir.slupphaug@ntnu.no 72573076 91825455 Laboratoriesenteret, 231.05.034, Øya, Erling Skjalgssons g 1 |
contact email | geir.slupphaug@ntnu.no |
lab head | |
Animesh Sharma |
contact affiliation | Engineer at NTNU, Norway |
contact email | sharma.animesh@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/03/PXD009135 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD009135
- Label: PRIDE project
- Name: Identification of adsorbing human plasma proteins on alginate gel beads