PXD009131 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomics analysis of human islets treated with IL-1b and IFN-g |
| Description | Human islets were treated with IL-1b and IFN-g for 24h, digested with trypsin, multiplexed with TMT-10, fractionated by high pH reverse-phase chromatography and analyzed by tandem LC-MS/MS. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-03-23 |
| AnnouncementXML | Submission_2026-03-23_03:20:45.096.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Ernesto Nakayasu |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | monohydroxylated residue |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2018-03-07 23:46:23 | ID requested | |
| 1 | 2019-10-25 00:23:42 | announced | |
| 2 | 2024-10-22 04:43:42 | announced | 2024-10-22: Updated project metadata. |
| ⏵ 3 | 2026-03-23 03:20:46 | announced | 2026-03-23: Updated project metadata. |
Publication List
| 10.1016/j.cmet.2019.12.005; |
| Nakayasu ES, Syed F, Tersey SA, Gritsenko MA, Mitchell HD, Chan CY, Dirice E, Turatsinze JV, Cui Y, Kulkarni RN, Eizirik DL, Qian WJ, Webb-Robertson BM, Evans-Molina C, Mirmira RG, Metz TO, Comprehensive Proteomics Analysis of Stressed Human Islets Identifies GDF15 as a Target for Type 1 Diabetes Intervention. Cell Metab, 31(2):363-374.e6(2020) [pubmed] |
Keyword List
| curator keyword: Biomedical |
| submitter keyword: proteomics, TMT-10, cytokines,Human islets, type 1 diabetes, cell death |
Contact List
| Tom Metz |
|---|
| contact affiliation | Biological Sciences Division, Pacific Northwest National Laboratory |
| contact email | thomas.metz@pnnl.gov |
| lab head | |
| Ernesto Nakayasu |
|---|
| contact affiliation | Pacific Northwest National Laboratory |
| contact email | ernesto.nakayasu@pnnl.gov |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/10/PXD009131 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD009131
- Label: PRIDE project
- Name: Proteomics analysis of human islets treated with IL-1b and IFN-g
