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PXD009128

PXD009128 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleHuman mitochondrial cysteine desulfurase complex data set 2
DescriptionCysteine desulfurase plays central role in mitochondrial iron-sulfur cluster biogenesis not only by providing sulfur through the catalysis of L-cysteine to L-alanine but also by serving as the platform for the assembly of other components of the biosynthetic machinery, including ISCU, frataxin, and ferredoxin. Human mitochondrial cysteine desulfurase complex consists of a homodimer with three components: NFS1, ISD11 and acyl carrier protein (ACP). In this study we used chemical crosslinking coupled with tandem mass spectrometry (XC-MS) to investigate the structures of cysteine desulfurase complexes.
HostingRepositoryPRIDE
AnnounceDate2022-03-25
AnnouncementXMLSubmission_2022-03-25_05:18:57.330.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD009128
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterKai Cai
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListDeamidated; Oxidation; Carbamidomethyl
InstrumentLTQ Orbitrap Elite
Dataset History
RevisionDatetimeStatusChangeLog Entry
02018-03-07 05:21:54ID requested
12022-03-25 05:18:57announced
Publication List
Dataset with its publication pending
Keyword List
curator keyword: Biological
submitter keyword: mitochondrial cysteine desulfurase, XC-MS
Contact List
John L. Markley
contact affiliationDepartment of Biochemistry University of Wisconsin-Madison
contact emailmarkley@biochem.wisc.edu
lab head
Kai Cai
contact affiliationUniversity of Wisconsin-Madison
contact emailkcai@wisc.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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