PXD009128 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Human mitochondrial cysteine desulfurase complex data set 2 |
Description | Cysteine desulfurase plays central role in mitochondrial iron-sulfur cluster biogenesis not only by providing sulfur through the catalysis of L-cysteine to L-alanine but also by serving as the platform for the assembly of other components of the biosynthetic machinery, including ISCU, frataxin, and ferredoxin. Human mitochondrial cysteine desulfurase complex consists of a homodimer with three components: NFS1, ISD11 and acyl carrier protein (ACP). In this study we used chemical crosslinking coupled with tandem mass spectrometry (XC-MS) to investigate the structures of cysteine desulfurase complexes. |
HostingRepository | PRIDE |
AnnounceDate | 2022-03-25 |
AnnouncementXML | Submission_2022-03-25_05:18:57.330.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD009128 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Kai Cai |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | Deamidated; Oxidation; Carbamidomethyl |
Instrument | LTQ Orbitrap Elite |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2018-03-07 05:21:54 | ID requested | |
⏵ 1 | 2022-03-25 05:18:57 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
curator keyword: Biological |
submitter keyword: mitochondrial cysteine desulfurase, XC-MS |
Contact List
John L. Markley |
contact affiliation | Department of Biochemistry University of Wisconsin-Madison |
contact email | markley@biochem.wisc.edu |
lab head | |
Kai Cai |
contact affiliation | University of Wisconsin-Madison |
contact email | kcai@wisc.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/03/PXD009128 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD009128
- Label: PRIDE project
- Name: Human mitochondrial cysteine desulfurase complex data set 2