PXD009051

PXD009051 is an original dataset announced via ProteomeXchange.

Title	Identification of UFBP1 interacting proteins
Description	UFBP1 (UFM1-binding and PCI domain-containing protein 1, also called DDRGK domain-containing protein 1, Dashurin, or C20orf116) is a protein that also participates in the ufmylation conjugating systems besides the E1 ubiquitin-like modifier-activating enzyme 5 (UBA5), the E2, UFM1-conjugating enzyme 1 (UFC1), and the E3, UFM1-protein ligase 1 (UFL1). Although this protein play important roles in the ufmylation, its other biological functions have not been explored. To identify the UFBP1 interacting proteins, we expressed GFP (control sample) and FLAG-UFBP1 (experimental sample) in HEK293T cells and purified UFBP1 and its interacting proteins for MS analysis.
HostingRepository	PRIDE
AnnounceDate	2018-05-08
AnnouncementXML	Submission_2018-05-08_05:25:59.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Dan Li
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2018-02-27 05:07:31	ID requested
⏵ 1	2018-05-08 05:26:00	announced

Zhu Y, Lei Q, Li D, Zhang Y, Jiang X, Hu Z, Xu G, Proteomic and Biochemical Analyses Reveal a Novel Mechanism for Promoting Protein Ubiquitination and Degradation by UFBP1, a Key Component of Ufmylation. J Proteome Res, 17(4):1509-1520(2018) [pubmed]

curator keyword: Biological

submitter keyword: UFBP1, interacting proteins, 293T, homo sapiens, orbitrap

Guoqiang Xu
contact affiliation	College of Pharmaceutical Sciences Soochow University Yunxuan Building 1328 199 Ren'ai Road, Suzhou, Jiangsu 215123, China
contact email	gux2002@suda.edu.cn
lab head
Dan Li
contact affiliation	Soochow University
contact email	445220956@qq.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/05/PXD009051

PRIDE project URI

• PRIDE
  1. PXD009051
     1. Label: PRIDE project
     2. Name: Identification of UFBP1 interacting proteins