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PXD009048

PXD009048 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleBloodstream infection N-glycoproteomics
DescriptionHere we have performed targeted quantitative N-glycoproteomics from plasma samples of patients with confirmed positive blood culture together with age and sex matched febrile controls with negative blood culture reports. Three hundred and sixty eight potential N-glycopeptides were quantified by mass spectrometry and 149 were further selected for identification. Twenty four N-glycopeptides were identified with high confidence together with elucidation of the peptide sequence, N-glycosylation site, glycan composition and proposed glycan structures. these N-glycopeptides can be used as potential biomarkers of bloodstream infection.
HostingRepositoryPRIDE
AnnounceDate2018-04-09
AnnouncementXMLSubmission_2018-04-09_01:06:55.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterSakari Joenväärä
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListiodoacetamide derivatized residue
InstrumentSynapt MS
Dataset History
RevisionDatetimeStatusChangeLog Entry
02018-02-27 02:09:58ID requested
12018-04-09 01:06:56announced
Publication List
Joenvaara S, Saraswat M, Kuusela P, Saraswat S, Agarwal R, Kaartinen J, J, ä, rvinen A, Renkonen R, Quantitative N-glycoproteomics reveals altered glycosylation levels of various plasma proteins in bloodstream infected patients. PLoS One, 13(3):e0195006(2018) [pubmed]
Keyword List
curator keyword: Biomedical
submitter keyword: Bloodstream infection, Sepsis, N-Glycoproteomics, Human plasma
Contact List
Risto Renkonen
contact affiliationTransplantation laboratory, Haartmaninkatu 3, PO Box 21, FI-00014 University of Helsinki, Finland. And HUSLAB, Helsinki University Hospital, Finland.
contact emailristo.renkonen@helsinki.fi
lab head
Sakari Joenväärä
contact affiliationHelsinki University
contact emailsakari.joenvaara@helsinki.fi
dataset submitter
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Dataset FTP location
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PRIDE project URI
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