PXD009039

PXD009039 is an original dataset announced via ProteomeXchange.

Title	Dissecting the malaria interactome
Description	To identify malaria protein interactions systematically we combined blue native polyacrylamide electrophoresis fractionation with quantitative mass spectrometry and machine learning. Our integrative approach identified over twenty thousand protein interactions in Plasmodium schizonts, organized into 600 complexes, the majority of which are novel, and generated a high-confidence Plasmodium protein interaction network.
HostingRepository	PRIDE
AnnounceDate	2019-08-06
AnnouncementXML	Submission_2019-08-12_01:35:28.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	James Wright
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue; deamidated residue
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2018-02-26 06:29:01	ID requested
1	2019-08-06 05:15:31	announced
⏵ 2	2019-08-12 01:35:29	announced	Updated publication reference for PubMed record(s): 31390575.

Hillier C, Pardo M, Yu L, Bushell E, Sanderson T, Metcalf T, Herd C, Anar B, Rayner JC, Billker O, Choudhary JS, Landscape of the Plasmodium Interactome Reveals Both Conserved and Species-Specific Functionality. Cell Rep, 28(6):1635-1647.e5(2019) [pubmed]

curator keyword: Biological, Biomedical

submitter keyword: malaria, interactome, blue native PAGE, Plasmodium, P. berghei, P. falciparum, P. knowlesi, protein-protein interactions, fractionation, multiprotein complexes, schizont

Jyoti Choudhary
contact affiliation	Wellcome Trust Sanger Institute
contact email	jc4@sanger.ac.uk
lab head
James Wright
contact affiliation	Functional Proteomics, Institute Cancer Research & Proteomic Mass Spectrometry, Wellcome Trust Sanger Institute
contact email	jw13@sanger.ac.uk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/08/PXD009039

PRIDE project URI

• PRIDE
  1. PXD009039
     1. Label: PRIDE project
     2. Name: Dissecting the malaria interactome