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PXD009007

PXD009007 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleHIV/HCV co-infection proteomics
DescriptionHepatic complications of HCV infection, including fibrosis and cirrhosis are accelerated in HIV-infected individuals. Although liver biopsy remains the gold standard for staging HCV-associated liver disease, this test can result in serious complications and is subject to sampling error. These challenges have prompted a search for non-invasive methods for liver fibrosis staging. To this end, we compared serum proteome profiles at different stages of fibrosis in HIV/HCV co- and HCV mono-infected patients using SELDI-TOF MS.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_04:42:57.354.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMomar Ndao
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
Instrument4800 Proteomics Analyzer
Dataset History
RevisionDatetimeStatusChangeLog Entry
02018-02-21 09:17:53ID requested
12018-04-09 01:33:14announced
22024-10-22 04:43:02announced2024-10-22: Updated project metadata.
Publication List
Golizeh M, Melendez-Pena CE, Ward BJ, Saeed S, Santamaria C, Conway B, Cooper C, Klein MB, Ndao M, Proteomic fingerprinting in HIV/HCV co-infection reveals serum biomarkers for the diagnosis of fibrosis staging. PLoS One, 13(4):e0195148(2018) [pubmed]
10.1371/journal.pone.0195148;
Keyword List
curator keyword: Biological
submitter keyword: SELDI, proteomics, HCV, co-infection, liver, fibrosis, HIV, MALDI, biomarker discovery,human
Contact List
Momar Ndao
contact affiliationDepartment of Medicine, McGill University, Montreal, Quebec, Canada
contact emailmomar.ndao@mcgill.ca
lab head
Momar Ndao
contact affiliationMcGill University
contact emailmomar.ndao@mcgill.ca
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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