PXD009000

PXD009000 is an original dataset announced via ProteomeXchange.

Title	Identification of MS-Cleavable and Non-Cleavable Chemically Crosslinked Peptides with MetaMorpheus
Description	The present work describes a novel search program for the detection of both MS-cleavable and non-cleavable crosslinked peptides and it is the first software program reported with both capacities. The search strategy has been implemented in the computer program MetaMorpheus, which has a user-friendly graphical user interface (GUI). Novel crosslinker molecules can be easily added if desired. A fragment-ion index scheme makes the search computationally efficient. DSSO crosslinked BSA and E.coli ribosome data were used to validate the MS-cleavable crosslink search results.
HostingRepository	PRIDE
AnnounceDate	2018-07-16
AnnouncementXML	Submission_2018-07-16_03:39:57.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Lei Lu
SpeciesList	scientific name: Escherichia coli; NCBI TaxID: 562;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2018-02-21 02:33:00	ID requested
⏵ 1	2018-07-16 03:39:58	announced

Dataset with its publication pending

curator keyword: Technical

submitter keyword: proteomics, MS-cleavable chemical crosslink, protein-protein interactions, ion index

Lloyd M Smith
contact affiliation	Department of Chemistry, University of Wisconsin, Madison, Wisconsin 53706, United States
contact email	smith@chem.wisc.edu
lab head
Lei Lu
contact affiliation	University of Wisconsin, Madison
contact email	llu56@wisc.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/07/PXD009000

PRIDE project URI

• PRIDE
  1. PXD009000
     1. Label: PRIDE project
     2. Name: Identification of MS-Cleavable and Non-Cleavable Chemically Crosslinked Peptides with MetaMorpheus