PXD008989 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | PROTEOMIC ANALYSIS OF EARLY DIABETIC RETINOPATHY REVEALS MEDIATORS OF NEURODEGENERATIVE BRAIN DISEASES |
Description | The aim of the present study was to identify early changes in diabetic retinas using an unbiased proteomics approach. Proteomic profiles of control retinas were compared to diabetic retinas obtained from patients known to have no classic vascular lesions that clinically define diabetic retinas. The diabetic retinas were further split into two groups according to the presence or absence of glial activation as marker of progressive changes that may be associated with the early neurodegenerative process. By examining differentially expressed proteins at this preclinical stage, our aim was to acquire a clearer understanding of the complex cellular processes that initiate diabetic retinas. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_08:49:21.209.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD008989 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Tatiana Laremore |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | Carbamidomethyl |
Instrument | LTQ Orbitrap Velos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2018-02-20 01:31:18 | ID requested | |
1 | 2022-03-02 02:27:47 | announced | |
⏵ 2 | 2023-11-14 08:49:21 | announced | 2023-11-14: Updated project metadata. |
Publication List
Keyword List
curator keyword: Biomedical |
submitter keyword: human retina, diabetes |
Contact List
Jeffrey M. Sundstrom |
contact affiliation | Penn State Eye Center, Penn State College of Medicine, Hershey Pennsylvania, USA |
contact email | jsundstrom@pennstatehealth.psu.edu |
lab head | |
Tatiana Laremore |
contact affiliation | Penn State |
contact email | tnl1@psu.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/03/PXD008989 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD008989
- Label: PRIDE project
- Name: PROTEOMIC ANALYSIS OF EARLY DIABETIC RETINOPATHY REVEALS MEDIATORS OF NEURODEGENERATIVE BRAIN DISEASES