PXD008959

PXD008959 is an original dataset announced via ProteomeXchange.

Title	SCI1 co-purifies with the STRIPAK protein PRO11
Description	The STRIPAK complex is a conserved multi-protein complex, which is found in animals and in fungi but not in prokaryotes and plants. It is involved in growth and development, regulating signal transduction in cellular pathways, for example hippo and MAPK, and it has a role in human neuronal diseases, cell fusion, and cancer (1, 2). Small coiled-coil (CC) proteins were described in the STRIPAK complex of humans, in the Far complex of S. cerevisiae, in the SIP complex of S. pombe and in the STRIPAK complex of D. melanogaster (dSTRIPAK) (3-8). However, the function of small CC proteins in the STRIPAK complex is poorly investigated. We identified SCI1, a small CC protein belonging to the STRIPAK complex in the filamentous ascomycete S. macrospora. As all other STRIPAK components, SCI1 is required for development, hyphal fusion and vegetative growth.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:43:03.170.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Oliver Valerius
SpeciesList	scientific name: Sordaria macrospora k-hell; NCBI TaxID: 771870;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2018-02-14 07:05:24	ID requested
1	2018-08-21 02:20:19	announced
2	2018-11-13 23:46:14	announced	Updated publication reference for PubMed record(s): 30107058.
⏵ 3	2024-10-22 04:43:11	announced	2024-10-22: Updated project metadata.

J Reschka E, Nordzieke S, Valerius O, Braus GH, P, ö, ggeler S, A novel STRIPAK complex component mediates hyphal fusion and fruiting-body development in filamentous fungi. Mol Microbiol, 110(4):513-532(2018) [pubmed]

10.1111/mmi.14106;

curator keyword: Biological

submitter keyword: STRIPAK, fruiting-body development, SCI1, PRO11, hyphal fusion, Sordaria macrospora

Stefanie Pöggeler
contact affiliation	Georg-August University, Institute of Microbiology and Genetics, Grisebachstr. 8, D-37077 Göttingen, Germany
contact email	spoegge@gwdg.de
lab head
Oliver Valerius
contact affiliation	Georg-August-Universität Göttingen
contact email	ovaleri@gwdg.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/08/PXD008959

PRIDE project URI

• PRIDE
  1. PXD008959
     1. Label: PRIDE project
     2. Name: SCI1 co-purifies with the STRIPAK protein PRO11