PXD008937

PXD008937 is an original dataset announced via ProteomeXchange.

Title	Impact of CD74 knockdown on the HLA peptidome of the H1 melanoma cell line
Description	The influence of CD74 expression on the HLA peptidome of the H1 melanoma cell line was analyzed by label-free quantitation mass spectrometry of HLA ligand extracts obtained from CD74 siRNA & control siRNA treated cells.
HostingRepository	PRIDE
AnnounceDate	2018-03-01
AnnouncementXML	Submission_2018-03-07_23:58:54.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Daniel Kowalewski
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2018-02-13 01:20:24	ID requested
1	2018-03-01 06:06:20	announced
⏵ 2	2018-03-07 23:58:55	announced	Updated publication reference for PubMed record(s): 29490700.

Zeiner PS, Zinke J, Kowalewski DJ, Bernatz S, Tichy J, Ronellenfitsch MW, Thorsen F, Berger A, Forster MT, Muller A, Steinbach JP, Beschorner R, Wischhusen J, Kvasnicka HM, Plate KH, Stefanovi, ć S, Weide B, Mittelbronn M, Harter PN, CD74 regulates complexity of tumor cell HLA class II peptidome in brain metastasis and is a positive prognostic marker for patient survival. Acta Neuropathol Commun, 6(1):18(2018) [pubmed]

curator keyword: Biomedical

submitter keyword: HLA peptidome, CD74, melanoma

Stefan Stevanovic
contact affiliation	University of Tübingen Interfaculty Institute for Cell Biology Department of Immunology
contact email	stefan.stevanovic@uni-tuebingen.de
lab head
Daniel Kowalewski
contact affiliation	University of Tuebingen, Department of Immunology
contact email	dercove@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/03/PXD008937

PRIDE project URI

• PRIDE
  1. PXD008937
     1. Label: PRIDE project
     2. Name: Impact of CD74 knockdown on the HLA peptidome of the H1 melanoma cell line