PXD008932

PXD008932 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	BRAF and IKKα involvement in DNA Damage Response
Description	BRAF and IKKα are damage-responsive kinases required for 53BP1 and RIF1 co-recruitment to sites of DNA breaks and for timely resolution of DNA lesions. This provides a novel therapeutic opportunity based on combining BRAF or IKKα inhibitors with therapeutic agents that induce DNA damage
HostingRepository	PRIDE
AnnounceDate	2019-11-14
AnnouncementXML	Submission_2019-11-14_00:51:37.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Eva Borràs
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	phosphorylated residue
Instrument	Orbitrap Fusion Lumos; LTQ Orbitrap Velos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2018-02-12 07:56:48	ID requested
⏵ 1	2019-11-14 00:55:13	announced

Publication List

Colomer C, Margalef P, Villanueva A, Vert A, Pecharroman I, Sol, é L, Gonz, á, lez-Farr, é M, Alonso J, Montagut C, Martinez-Iniesta M, Bertran J, Borr, à, s E, Iglesias M, Sabid, ó E, Bigas A, Boulton SJ, Espinosa L, Kinase Regulates the DNA Damage Response and Drives Chemo-resistance in Cancer. Mol Cell, 75(4):669-682.e5(2019) [pubmed]

Colomer C, Margalef P, Villanueva A, Vert A, Pecharroman I, Sol, é L, Gonz, á, lez-Farr, é M, Alonso J, Montagut C, Martinez-Iniesta M, Bertran J, Borr, à, s E, Iglesias M, Sabid, ó E, Bigas A, Boulton SJ, Espinosa L, Kinase Regulates the DNA Damage Response and Drives Chemo-resistance in Cancer. Mol Cell, 75(4):669-682.e5(2019) [pubmed]

Keyword List

curator keyword: Biomedical
submitter keyword: BRAF, Ikka, DNAdamage, colorectal cancer

curator keyword: Biomedical

submitter keyword: BRAF, Ikka, DNAdamage, colorectal cancer

Contact List

Eduard Sabido
contact affiliation	Center for Genomic Regulation (CRG), University Pompeu Fabra (UPF)
contact email	eduard.sabido@crg.eu
lab head
Eva Borràs
contact affiliation	UPF
contact email	eva.borras@upf.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/11/PXD008932
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/11/PXD008932

PRIDE project URI

Repository Record List

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