PXD008745 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | N-glycoproteomic analyses from different insect species reveal conserved and unique glycoproteins |
Description | N-glycosylation is one of the most abundant and conserved protein modifications in eukaryotes. This modification serves various important functions, such as protein folding and cellular attachment, but also modulation of a protein’s function. Recently, it has been shown that N-glycosylation of proteins plays a vital role in insect development and survival, which makes it an interesting target for pest control. Despite the importance of protein N-glycosylation in insects, not much is known about insect N-glycoproteomes. Here, we report on the N-glycoproteomes of three major pest insects spanning different insect orders; Drosophila melanogaster (Diptera), Tribolium castaneum (Coleoptera) and Acyrthosiphon pisum (Hemiptera). The number of identified N-glycosylation sites ranged from 889 in T. castaneum, to 941 in D. melanogaster and 1,338 in A. pisum. Comparison between the different insect species revealed both conserved and species-specific glycoproteins. The functionality of the insect glycoproteins together with the conservation of the N-glycosites throughout evolution are discussed. This information can help in the elaboration of novel pest insect control strategies based on interference in insect glycosylation. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_04:04:13.096.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | An Staes |
SpeciesList | scientific name: Tetropium castaneum; NCBI TaxID: 256648; scientific name: Buchnera aphidicola subsp. Acyrthosiphon pisum (Acyrthosiphon pisum symbiotic bacterium); NCBI TaxID: 118099; scientific name: Drosophila melanogaster (Fruit fly); NCBI TaxID: 7227; |
ModificationList | deamidated residue |
Instrument | Q Exactive HF; LTQ Orbitrap Velos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2018-01-24 02:30:45 | ID requested | |
1 | 2018-06-18 01:15:07 | announced | |
⏵ 2 | 2024-10-22 04:04:15 | announced | 2024-10-22: Updated project metadata. |
Publication List
Scheys F, Van Damme EJM, De Schutter K, Staes A, Gevaert K, Smagghe G, Evolutionarily conserved and species-specific glycoproteins in the N-glycoproteomes of diverse insect species. Insect Biochem Mol Biol, 100():22-29(2018) [pubmed] |
10.1016/j.ibmb.2018.04.011; |
Keyword List
curator keyword: Biological |
submitter keyword: glycoprotein, mass spectrometry (MS), proteomics,Drosophila melanogaster, insect, pest insect, lectin, N-linked glycosylation |
Contact List
Guy Smagghe |
contact affiliation | Department of Crop Protection, Faculty of Bioscience Engineering, Ghent University, Coupure links 653, B-9000 Ghent,Belgium |
contact email | guy.smagghe@ugent.be |
lab head | |
An Staes |
contact affiliation | Medical Protein Chemistry |
contact email | an.staes@vib-ugent.be |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD008745
- Label: PRIDE project
- Name: N-glycoproteomic analyses from different insect species reveal conserved and unique glycoproteins