PXD008666

PXD008666 is an original dataset announced via ProteomeXchange.

Title	Tracking the N-Myristoylated N-termini in human cell line lysates (soluble fraction) to highlight this protein modification at the proteome level
Description	Characterization of N-Myristoylated proteins in the soluble fraction of four human cell lines (HUVEC, U87, K562 and HCT116) using large-scale proteomics approaches.
HostingRepository	PRIDE
AnnounceDate	2018-06-18
AnnouncementXML	Submission_2018-06-18_03:06:08.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Willy Bienvenut
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetate labeling reagent (N-term) (heavy form: +3amu); palmitoylated residue; 3x(2)H labeled N6-acetyl-L-lysine; myristoylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2018-01-12 06:09:26	ID requested
⏵ 1	2018-06-18 03:06:09	announced

Castrec B, Dian C, Ciccone S, Ebert CL, Bienvenut WV, Le Caer JP, Steyaert JM, Giglione C, Meinnel T, Structural and genomic decoding of human and plant myristoylomes reveals a definitive recognition pattern. Nat Chem Biol, 14(7):671-679(2018) [pubmed]

curator keyword: Biological

submitter keyword: N-terminus, Myristoylation, S-palmitoylation, methionine excision, N-acetylation, N-myristoyltransferase

Willy Bienvenut
contact affiliation	Institute of Integrative Biology of the Cell (I2BC), CEA, CNRS, Université Paris-Sud, Avenue de la Terrasse, F-91198 Gif-sur-Yvette cedex, France ( lab head )
contact email	willy.bienvenut@i2bc.paris-saclay.fr
lab head
Willy Bienvenut
contact affiliation	CNRS
contact email	willy.bienvenut@i2bc.paris-saclay.fr
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/06/PXD008666

PRIDE project URI

• PRIDE
  1. PXD008666
     1. Label: PRIDE project
     2. Name: Tracking the N-Myristoylated N-termini in human cell line lysates (soluble fraction) to highlight this protein modification at the proteome level