PXD008605

PXD008605 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Cryo-EM structure of the full human PRC2 and regulation by AEBP2 and JARID2
Description	Structural study of the PRC2 complex and its regulators AEPB2 and JARID2 combining cryo-EM, cross-linking, targeted MS and hydrogen/deuterium exchange MS.
HostingRepository	PRIDE
AnnounceDate	2018-01-25
AnnouncementXML	Submission_2018-01-25_04:23:32.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Marco Faini
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2018-01-08 00:03:53	ID requested
⏵ 1	2018-01-25 04:23:33	announced

Publication List

Kasinath V, Faini M, Poepsel S, Reif D, Feng XA, Stjepanovic G, Aebersold R, Nogales E, Structures of human PRC2 with its cofactors AEBP2 and JARID2. Science, 359(6378):940-944(2018) [pubmed]

Kasinath V, Faini M, Poepsel S, Reif D, Feng XA, Stjepanovic G, Aebersold R, Nogales E, Structures of human PRC2 with its cofactors AEBP2 and JARID2. Science, 359(6378):940-944(2018) [pubmed]

Keyword List

curator keyword: Biological
submitter keyword: Chemical cross-linking, XL-MS, DSS, structural proteomics, integrative stuctural biology, cryo-EM, PRC2, chromatin

curator keyword: Biological

submitter keyword: Chemical cross-linking, XL-MS, DSS, structural proteomics, integrative stuctural biology, cryo-EM, PRC2, chromatin

Contact List

Ruedi Aebersold
contact affiliation	Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, 8093, Zurich, Switzerland
contact email	aebersold@imsb.biol.ethz.ch
lab head
Marco Faini
contact affiliation	ETH Zurich
contact email	faini@imsb.biol.ethz.ch
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/01/PXD008605
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/01/PXD008605

PRIDE project URI

Repository Record List

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