PXD008575

PXD008575 is an original dataset announced via ProteomeXchange.

Title	Mammalian proteome changes during oxidative stress and stress of the endoplasmic reticulum
Description	Stress due to protein misfolding in the endoplasmic reticulum affects transcription and translation, RNA and protein degradation. By integrating several large-scale datasets, we quantified transcription, translation, RNA-protein binding events, and protein levels for several thousands of genes in HeLa cells. Here, we deposit the TMT-based, quantitative proteomics data consisting of two replicates with four measured time points collected for two stress treatments, i.e. tunicamycin and hydrogen peroxide.
HostingRepository	PRIDE
AnnounceDate	2018-10-12
AnnouncementXML	Submission_2018-10-12_00:30:24.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Shuvadeep Maity
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos; Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2018-01-02 05:25:40	ID requested
1	2018-10-11 09:57:37	announced
⏵ 2	2018-10-12 00:30:26	announced	Updated project metadata.

Rendleman J, Cheng Z, Maity S, Kastelic N, Munschauer M, Allgoewer K, Teo G, Zhang YBM, Lei A, Parker B, Landthaler M, Freeberg L, Kuersten S, Choi H, Vogel C, New insights into the cellular temporal response to proteostatic stress. Elife, 7():(2018) [pubmed]

curator keyword: Biological, Biomedical

submitter keyword: ER stress, Oxidative stress, Translation, Proteomics

Christine Vogel
contact affiliation	New York University - Department of Biology, Center for Genomics & Systems Biology , New York, USA
contact email	cvogel@nyu.edu
lab head
Shuvadeep Maity
contact affiliation	Associate research Scientist
contact email	sm6622@nyu.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/10/PXD008575

PRIDE project URI

• PRIDE
  1. PXD008575
     1. Label: PRIDE project
     2. Name: Mammalian proteome changes during oxidative stress and stress of the endoplasmic reticulum