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PXD008479

PXD008479 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePalaeoproteomic profiles of Iron Age teeth from Northwest Thailand
DescriptionHuman skeletal tissue contains an abundance of proteins some of which may be preserved over geological timescales. The profiling of proteins from ancient individuals — or palaeoproteomics —has begun to provide new information about the diseases suffered in past societies. We describe here the first dental palaeoproteomic profiles of Iron Age individuals, collected from the site of Long Long Rak rockshelter in northwest Thailand. We recovered amino acid sequences for thousands of proteins preserved in their dental tissue, however, it is evident that these palaeoproteomic profiles comprise a palimpsest of modifications that occurred both ante-mortem and post-mortem. Palaeoproteomic profiles are able to categorise disease and show the capacity of these individuals for harboring a variety of illnesses prior to death. Here we apply for the first time palaeoproteomic analysis to five prehistoric human teeth from Southeast Asia. We combine this method with stable isotope analysis using δ18O and δ13C values to broadly identify the diet of these individuals. The specimens were collected from log coffins contained within the Iron Age site of Long Long Rak (LLR) rockshelter in Pang Mapha district, Mae Hong Son Province, northwest Thailand.. Radiocarbon dating shows these log coffins to date within the range of 1,960±30 cal. yr BP to 1,636±44 cal. yr BP.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_04:42:50.206.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterValerie Wasinger
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonohydroxylated residue
InstrumentLTQ Orbitrap Velos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02017-12-18 01:47:09ID requested
12019-11-20 06:23:45announced
22024-10-22 04:42:52announced2024-10-22: Updated project metadata.
Publication List
Wasinger VC, Curnoe D, Bustamante S, Mendoza R, Shoocongdej R, Adler L, Baker A, Chintakanon K, Boel C, Tacon PSC, Analysis of the Preserved Amino Acid Bias in Peptide Profiles of Iron Age Teeth from a Tropical Environment Enable Sexing of Individuals Using Amelogenin MRM. Proteomics, 19(5):e1800341(2019) [pubmed]
10.1002/pmic.201800341;
Keyword List
curator keyword: Biological
submitter keyword: human,teeth, paleoproteome
Contact List
Valerie Wasinger
contact affiliationBioanalytical Mass Spectrometry Facility Mark Wainwright Analytical Centre. Room 404B, Lv4 Wallace Wurth Building C27 UNSW Australia www.bmsf.unsw.edu.au Affiliated with: Paleontology, Geobiology and Earth Archives Research Centre (PANGEA) http://www.pangea.unsw.edu.au/
contact emailv.wasinger@unsw.edu.au
lab head
Valerie Wasinger
contact affiliationUNSW
contact emailv.wasinger@unsw.edu.au
dataset submitter
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Dataset FTP location
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