PXD008479

PXD008479 is an original dataset announced via ProteomeXchange.

Title	Palaeoproteomic profiles of Iron Age teeth from Northwest Thailand
Description	Human skeletal tissue contains an abundance of proteins some of which may be preserved over geological timescales. The profiling of proteins from ancient individuals — or palaeoproteomics —has begun to provide new information about the diseases suffered in past societies. We describe here the first dental palaeoproteomic profiles of Iron Age individuals, collected from the site of Long Long Rak rockshelter in northwest Thailand. We recovered amino acid sequences for thousands of proteins preserved in their dental tissue, however, it is evident that these palaeoproteomic profiles comprise a palimpsest of modifications that occurred both ante-mortem and post-mortem. Palaeoproteomic profiles are able to categorise disease and show the capacity of these individuals for harboring a variety of illnesses prior to death. Here we apply for the first time palaeoproteomic analysis to five prehistoric human teeth from Southeast Asia. We combine this method with stable isotope analysis using δ18O and δ13C values to broadly identify the diet of these individuals. The specimens were collected from log coffins contained within the Iron Age site of Long Long Rak (LLR) rockshelter in Pang Mapha district, Mae Hong Son Province, northwest Thailand.. Radiocarbon dating shows these log coffins to date within the range of 1,960±30 cal. yr BP to 1,636±44 cal. yr BP.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:42:50.206.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Valerie Wasinger
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2017-12-18 01:47:09	ID requested
1	2019-11-20 06:23:45	announced
⏵ 2	2024-10-22 04:42:52	announced	2024-10-22: Updated project metadata.

Wasinger VC, Curnoe D, Bustamante S, Mendoza R, Shoocongdej R, Adler L, Baker A, Chintakanon K, Boel C, Tacon PSC, Analysis of the Preserved Amino Acid Bias in Peptide Profiles of Iron Age Teeth from a Tropical Environment Enable Sexing of Individuals Using Amelogenin MRM. Proteomics, 19(5):e1800341(2019) [pubmed]

10.1002/pmic.201800341;

curator keyword: Biological

submitter keyword: human,teeth, paleoproteome

Valerie Wasinger
contact affiliation	Bioanalytical Mass Spectrometry Facility Mark Wainwright Analytical Centre. Room 404B, Lv4 Wallace Wurth Building C27 UNSW Australia www.bmsf.unsw.edu.au Affiliated with: Paleontology, Geobiology and Earth Archives Research Centre (PANGEA) http://www.pangea.unsw.edu.au/
contact email	v.wasinger@unsw.edu.au
lab head
Valerie Wasinger
contact affiliation	UNSW
contact email	v.wasinger@unsw.edu.au
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/11/PXD008479

PRIDE project URI

• PRIDE
  1. PXD008479
     1. Label: PRIDE project
     2. Name: Palaeoproteomic profiles of Iron Age teeth from Northwest Thailand