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PXD008467

PXD008467 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePlasma proteomics reveals the confounding effect of heparin administration on the analysis of candidate cardiovascular biomarkers - Cohort1
DescriptionSeveral plasma proteins have been suggested as markers for a variety of cardiovascular conditions but fail to qualify in independent patient cohorts. One reason may relate to interference of medication on plasma protein levels. In the present study we applied a proteomic approach to identify plasma proteins that changed in concentration with heparin administration and therefore potentially may confound their as biomarkers in situations where heparin is used.
HostingRepositoryPRIDE
AnnounceDate2025-02-09
AnnouncementXMLSubmission_2025-02-09_02:18:07.299.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterHans Christian Beck
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListTMT6plex-126 reporter+balance reagent acylated residue; monohydroxylated residue; iodoacetamide derivatized residue; deamidated residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02017-12-15 03:25:03ID requested
12018-10-02 04:58:43announced
22025-02-09 02:18:08announced2025-02-09: Updated project metadata.
Publication List
Beck HC, Jensen LO, Gils C, Ilondo AMM, Frydland M, Hassager C, M, ø, ller-Helgestad OK, M, ø, ller JE, Rasmussen LM, Proteomic Discovery and Validation of the Confounding Effect of Heparin Administration on the Analysis of Candidate Cardiovascular Biomarkers. Clin Chem, 64(10):1474-1484(2018) [pubmed]
10.1373/clinchem.2017.282665;
Keyword List
curator keyword: Biomedical
submitter keyword: heparin, chemi-proteomics, cardiovascular biomkarkers
Contact List
Hans Christian Beck
contact affiliationOdense University Hospital, Dept Clinical Biochemistry and Pharmacology, Odense, DK-5000, Denmark
contact emailhans.christian.beck@rsyd.dk
lab head
Hans Christian Beck
contact affiliationOdense University Hospital, Odense, Denmark
contact emailhans.christian.beck@rsyd.dk
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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