PXD008459 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Extensive identification and in-depth validation of importin 13 cargoes |
Description | Importin 13 is a bidirectional transport receptor that mediates both nuclear import and export of proteins. To expand the range of human importin 13 cargoes, we performed importin 13 binding experiments in combination with quantitative stable isotope labeling with amino acids in cell culture (SILAC) and mass spectrometry. Apart from known importin 13 interaction partners, such as Ubc9 and eIF1A, more than 300 potential importin 13 cargoes were identified, several of which could be validated using cellular and biochemical assays. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_04:42:51.498.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Oliver Valerius |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue |
Instrument | LTQ Orbitrap Velos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2017-12-15 00:36:38 | ID requested | |
1 | 2018-04-20 05:29:46 | announced | |
⏵ 2 | 2024-10-22 04:42:59 | announced | 2024-10-22: Updated project metadata. |
Publication List
Baade I, Spillner C, Schmitt K, Valerius O, Kehlenbach RH, Extensive Identification and In-depth Validation of Importin 13 Cargoes. Mol Cell Proteomics, 17(7):1337-1353(2018) [pubmed] |
10.1074/mcp.ra118.000623; |
Keyword List
curator keyword: Biological |
submitter keyword: importin 13, human, SILAC, nucleocytoplasmic transport, nuclear transport receptor |
Contact List
Ralph H. Kehlenbach |
contact affiliation | University Medical Center Göttingen, Department of Molecular Biology, Germany |
contact email | rkehlen@gwdg.de |
lab head | |
Oliver Valerius |
contact affiliation | Georg-August-Universität Göttingen |
contact email | ovaleri@gwdg.de |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/04/PXD008459 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD008459
- Label: PRIDE project
- Name: Extensive identification and in-depth validation of importin 13 cargoes