PXD008452

PXD008452 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Monocyte responses to Al(OH)3 adjuvant
Description	Monocytes, derived from three different donors, were stimulated with the vaccine adjuvant Al(OH)3 for 24 and 48 hours. Proteins were isolated and equal protein amounts were labeledusing TMT(6). We found that Al(OH)3 activates various pathways related to the innate immune response.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:42:07.893.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sietske Kooijman
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue; monohydroxylated residue; deamidated residue
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2017-12-14 03:22:06	ID requested
1	2018-03-27 00:30:51	announced
2	2018-03-27 02:57:57	announced	Updated project metadata.
⏵ 3	2024-10-22 04:42:15	announced	2024-10-22: Updated project metadata.

Publication List

10.1016/j.jprot.2017.12.021;
Kooijman S, Brummelman J, van Els CACM, Marino F, Heck AJR, Mommen GPM, Metz B, Kersten GFA, Pennings JLA, Meiring HD, Novel identified aluminum hydroxide-induced pathways prove monocyte activation and pro-inflammatory preparedness. J Proteomics, 175():144-155(2018) [pubmed]

10.1016/j.jprot.2017.12.021;

Kooijman S, Brummelman J, van Els CACM, Marino F, Heck AJR, Mommen GPM, Metz B, Kersten GFA, Pennings JLA, Meiring HD, Novel identified aluminum hydroxide-induced pathways prove monocyte activation and pro-inflammatory preparedness. J Proteomics, 175():144-155(2018) [pubmed]

Keyword List

curator keyword: Biomedical
submitter keyword: alum-based adjuvant, innate immune response, quantitative proteomics

curator keyword: Biomedical

submitter keyword: alum-based adjuvant, innate immune response, quantitative proteomics

Contact List

Hugo Meiring
contact affiliation	Intravacc; Bilthoven; the Netherlands
contact email	hugo.meiring@intravacc.nl
lab head
Sietske Kooijman
contact affiliation	Intravacc
contact email	sietske.kooijman@intravacc.nl
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/03/PXD008452
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/03/PXD008452

PRIDE project URI

Repository Record List

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