PXD008452 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Monocyte responses to Al(OH)3 adjuvant |
Description | Monocytes, derived from three different donors, were stimulated with the vaccine adjuvant Al(OH)3 for 24 and 48 hours. Proteins were isolated and equal protein amounts were labeledusing TMT(6). We found that Al(OH)3 activates various pathways related to the innate immune response. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_04:42:07.893.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Sietske Kooijman |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | TMT6plex-126 reporter+balance reagent acylated residue; monohydroxylated residue; deamidated residue |
Instrument | Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2017-12-14 03:22:06 | ID requested | |
1 | 2018-03-27 00:30:51 | announced | |
2 | 2018-03-27 02:57:57 | announced | Updated project metadata. |
⏵ 3 | 2024-10-22 04:42:15 | announced | 2024-10-22: Updated project metadata. |
Publication List
10.1016/j.jprot.2017.12.021; |
Kooijman S, Brummelman J, van Els CACM, Marino F, Heck AJR, Mommen GPM, Metz B, Kersten GFA, Pennings JLA, Meiring HD, Novel identified aluminum hydroxide-induced pathways prove monocyte activation and pro-inflammatory preparedness. J Proteomics, 175():144-155(2018) [pubmed] |
Keyword List
curator keyword: Biomedical |
submitter keyword: alum-based adjuvant, innate immune response, quantitative proteomics |
Contact List
Hugo Meiring |
contact affiliation | Intravacc; Bilthoven; the Netherlands |
contact email | hugo.meiring@intravacc.nl |
lab head | |
Sietske Kooijman |
contact affiliation | Intravacc |
contact email | sietske.kooijman@intravacc.nl |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/03/PXD008452 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD008452
- Label: PRIDE project
- Name: Monocyte responses to Al(OH)3 adjuvant