PXD008407 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | LC-MSMS analysis of human urine to identify early diagnostic biomarkers for prostate cancer |
Description | In order to detect proteins sensitive and specific enough to detect early stages of PCa, we performed a complex comparative proteomic study analyzing urine as a source for non-invasive biomarkers. We compared urine samples from patients with early PCa stages and Gleason score between 6 and 7 with samples from patients with BPH and other urological cancers, namely bladder and renal. The main goal of this study was to discover a diagnostic biomarker or set of biomarkers in urine, sufficiently sensitive to detect PCa in its early stages and specific enough to separate the disease from BPH or other urological cancers. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_04:36:30.002.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD008407 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Katarina Davalieva |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | Oxidation; Carbamidomethyl |
Instrument | Synapt MS |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2017-12-11 03:14:08 | ID requested | |
1 | 2018-01-02 03:32:57 | announced | |
⏵ 2 | 2024-10-22 04:36:38 | announced | 2024-10-22: Updated project metadata. |
Publication List
10.3390/proteomes6010001; |
10.6019/PXD008407; |
Davalieva K, Kiprijanovska S, Maleva Kostovska I, Stavridis S, Stankov O, Komina S, Petrusevska G, Polenakovic M, Comparative Proteomics Analysis of Urine Reveals Down-Regulation of Acute Phase Response Signaling and LXR/RXR Activation Pathways in Prostate Cancer. Proteomes, 6(1):(2017) [pubmed] |
Keyword List
curator keyword: Biomedical |
submitter keyword: Human, LC-MSMS, Prostate cancer, Urine, diagnostic biomarkers |
Contact List
Katarina Davalieva |
contact affiliation | Research Centre for Genetic Engineering and Biotechnology “Georgi D Efremov”, Department of Proteomics, Macedonian Academy of Sciences and Arts, Skopje, Krste Misirkov 2, 1000 Skopje, Republic of Macedonia |
contact email | katarina@manu.edu.mk |
lab head | |
Katarina Davalieva |
contact affiliation | Research Centre for Genetic Engineering and Biotechnology “Georgi D Efremov”, Macedonian Academy of Sciences and Arts, Skopje |
contact email | katarina@manu.edu.mk |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD008407
- Label: PRIDE project
- Name: LC-MSMS analysis of human urine to identify early diagnostic biomarkers for prostate cancer