PXD008407

PXD008407 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	LC-MSMS analysis of human urine to identify early diagnostic biomarkers for prostate cancer
Description	In order to detect proteins sensitive and specific enough to detect early stages of PCa, we performed a complex comparative proteomic study analyzing urine as a source for non-invasive biomarkers. We compared urine samples from patients with early PCa stages and Gleason score between 6 and 7 with samples from patients with BPH and other urological cancers, namely bladder and renal. The main goal of this study was to discover a diagnostic biomarker or set of biomarkers in urine, sufficiently sensitive to detect PCa in its early stages and specific enough to separate the disease from BPH or other urological cancers.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:36:30.002.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD008407
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Katarina Davalieva
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	Oxidation; Carbamidomethyl
Instrument	Synapt MS

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2017-12-11 03:14:08	ID requested
1	2018-01-02 03:32:57	announced
⏵ 2	2024-10-22 04:36:38	announced	2024-10-22: Updated project metadata.

Publication List

10.3390/proteomes6010001;
10.6019/PXD008407;
Davalieva K, Kiprijanovska S, Maleva Kostovska I, Stavridis S, Stankov O, Komina S, Petrusevska G, Polenakovic M, Comparative Proteomics Analysis of Urine Reveals Down-Regulation of Acute Phase Response Signaling and LXR/RXR Activation Pathways in Prostate Cancer. Proteomes, 6(1):(2017) [pubmed]

10.3390/proteomes6010001;

10.6019/PXD008407;

Davalieva K, Kiprijanovska S, Maleva Kostovska I, Stavridis S, Stankov O, Komina S, Petrusevska G, Polenakovic M, Comparative Proteomics Analysis of Urine Reveals Down-Regulation of Acute Phase Response Signaling and LXR/RXR Activation Pathways in Prostate Cancer. Proteomes, 6(1):(2017) [pubmed]

Keyword List

curator keyword: Biomedical
submitter keyword: Human, LC-MSMS, Prostate cancer, Urine, diagnostic biomarkers

curator keyword: Biomedical

submitter keyword: Human, LC-MSMS, Prostate cancer, Urine, diagnostic biomarkers

Contact List

Katarina Davalieva
contact affiliation	Research Centre for Genetic Engineering and Biotechnology “Georgi D Efremov”, Department of Proteomics, Macedonian Academy of Sciences and Arts, Skopje, Krste Misirkov 2, 1000 Skopje, Republic of Macedonia
contact email	katarina@manu.edu.mk
lab head
Katarina Davalieva
contact affiliation	Research Centre for Genetic Engineering and Biotechnology “Georgi D Efremov”, Macedonian Academy of Sciences and Arts, Skopje
contact email	katarina@manu.edu.mk
dataset submitter

Full Dataset Link List

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PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/01/PXD008407

PRIDE project URI

Repository Record List

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