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PXD008369

PXD008369 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleWidespread protein histidine phosphorylation in bacteria
DescriptionFor decades, extreme difficulties in analyzing histidine phosphorylation have limited the study of phosphohistidine signaling. Here we report a method revealing widespread and abundant protein histidine phosphorylation in E. coli. Our new approach generated the largest E. coli phosphoproteome dataset to date, of which a remarkable high percentage (~10%) are phosphohistidine sites. This resource enables a major step forward towards a better understanding of the biological function of histidine phosphorylation.
HostingRepositoryjPOST
AnnounceDate2017-12-07
AnnouncementXMLSubmission_2022-09-18_02:24:58.875.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMiao-Hsia Lin
SpeciesList scientific name: Escherichia coli; NCBI TaxID: 562;
ModificationListS-carboxamidomethyl-L-cysteine; L-methionine sulfoxide; phosphorylated L-histidine; O-phospho-L-serine; O-phospho-L-threonine; O4'-phospho-L-tyrosine
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02017-12-05 05:55:14ID requested
12017-12-07 01:15:53announced
22018-02-08 01:57:16announcedUpdated PubMed.
32018-09-19 00:44:44announcedUpdated CV, FTP location and Modification list.
42021-02-04 17:33:00announced2021-02-04: Updated FTP location.
52022-09-18 02:24:59announced2022-09-18: Updated FTP location.
Publication List
Potel CM, Lin MH, Heck AJR, Lemeer S, Widespread bacterial protein histidine phosphorylation revealed by mass spectrometry-based proteomics. Nat Methods, 15(3):187-190(2018) [pubmed]
Keyword List
submitter keyword: histidine phosphorylation, E. coli, phosphoproteome
Contact List
Albert J.R. Heck
lab head
Miao-Hsia Lin
contact affiliationInstitute of Chemistry, Academia Sinica
dataset submitter
Full Dataset Link List
jPOST dataset URI
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST000369/