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PXD008281 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleIdentifying PTMs on PERIOD over a circadian day in Drosophila melanogaster
DescriptionCircadian clocks coordinate time-of-day specific metabolic and physiological processes to maximize performance and fitness. In addition to light, which is considered the strongest time cue to entrain animal circadian clocks, metabolic input has emerged as an important signal for clock modulation and entrainment, especially in peripheral clocks. Circadian clock proteins have been to be substrates of O-GlcNAcylation, a nutrient sensitive post-translational modification (PTM), and the interplay between clock protein O-GlcNAcylation and other PTMs, like phosphorylation, is expected to facilitate the regulation of circadian physiology by metabolic signals. Here, we used mass spectrometry proteomics to identify PTMs on PERIOD, the key biochemical timer of the Drosophila clock, over the circadian cycle.
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJoanna Chiu
SpeciesList scientific name: Drosophila melanogaster; common name: fruit fly; NCBI TaxID: 7227;
InstrumentLTQ Orbitrap Velos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02017-11-23 14:25:42ID requested
12019-01-15 21:13:39announced
Publication List
no publication
Keyword List
submitter keyword: Drosophila PERIOD, circadian rhythms
Contact List
Joanna Chiu
contact affiliationUniversity of California, Davis
contact emailjcchiu@ucdavis.edu
lab head
Joanna Chiu
contact affiliationUniversity of California, Davis
contact emailyhli@ucdavis.edu
dataset submitter
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