PXD008267

PXD008267 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteomic profiling of human iPSC-derived pancreatic endocrine cells for the identification of clinical biomarkers
Description	Great progresses have been made for generating in vitro pluripotent stem cell pancreatic β-like cells. However, the maturation stage of the cells still requires in vivo maturation to recreate the environmental niche. A deeper understanding of the factors promoting maturation of the cells is of great interest for clinical applications. We performed label-free mass spectrometry-based proteomic analysis of samples from a longitudinal study of differentiation of human-induced pluripotent stem cells towards glucose-responsive insulin producing cells.
HostingRepository	PRIDE
AnnounceDate	2018-04-04
AnnouncementXML	Submission_2018-04-04_05:10:48.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD008267
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Loïc Dayon
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	Ammonia-loss; Deamidated; Dehydrated; Oxidation; Acetyl; Carbamidomethyl
Instrument	LTQ Orbitrap Elite

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2017-11-22 08:29:52	ID requested
⏵ 1	2018-04-04 05:10:49	announced

Publication List

Haller C, Chaskar P, Piccand J, Cominetti O, Macron C, Dayon L, Kraus MR, Insights into Islet Differentiation and Maturation through Proteomic Characterization of a Human iPSC-Derived Pancreatic Endocrine Model. Proteomics Clin Appl, 12(5):e1600173(2018) [pubmed]

Haller C, Chaskar P, Piccand J, Cominetti O, Macron C, Dayon L, Kraus MR, Insights into Islet Differentiation and Maturation through Proteomic Characterization of a Human iPSC-Derived Pancreatic Endocrine Model. Proteomics Clin Appl, 12(5):e1600173(2018) [pubmed]

Keyword List

curator keyword: Biomedical
submitter keyword: Beta-cell
Diabetes mellitus
Differentiation
Human
Mass spectrometry
Maturation
Proteomics
Pluripotent
Spectral counting
Stem cells
Therapy

curator keyword: Biomedical

submitter keyword: Beta-cell

Diabetes mellitus

Differentiation

Human

Mass spectrometry

Maturation

Proteomics

Pluripotent

Spectral counting

Stem cells

Therapy

Contact List

Marine Kraus
contact affiliation	Stem Cells, Nestlé Institute of Health Sciences, CH-1015 Lausanne, Switzerland
contact email	Marine.Kraus@rd.nestle.com
lab head
Loïc Dayon
contact affiliation	Nestlé Institute of Health Sciences SA
contact email	loic.dayon@rd.nestle.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/04/PXD008267
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/04/PXD008267

PRIDE project URI

Repository Record List

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