PXD008232

PXD008232 is an original dataset announced via ProteomeXchange.

Title	The effect of entomopathogenic fungal culture filtrate on the immune response and haemolymph proteome of the large pine weevil, Hylobius abietis.
Description	The large pine weevil Hylobius abietis L. is a major forestry pest in 15 European countries, where it is a threat to 3.4 million hectares of forest. A cellular and proteomic analysis of the effect of culture filtrate of three entomopathogenic fungi (EPF) species on the immune system of H. abietis was performed. Injection with Metarhizium anisopliae or Beauvaria bassiana culture showed significantly increased mortality highlighting that EPF culture filtrate has the potential to modulate the insect immune system allowing a subsequent pathogen to proliferate. Injection with EPF culture filtrate was shown to alter the abundance of protease inhibitors, detoxification enzymes, antimicrobial peptides and proteins involved in reception/detection and development in H. abietis larvae. Larvae injected with B. caledonica culture filtrate displayed significant alterations in abundance of proteins involved in cellulytic and other metabolic processes in their haemolymph proteome.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:41:50.566.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	James Carolan
SpeciesList	scientific name: Hylobius abietis; NCBI TaxID: 201999;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2017-11-17 08:37:43	ID requested
1	2018-07-23 09:00:11	announced
⏵ 2	2024-10-22 04:41:52	announced	2024-10-22: Updated project metadata.

10.1016/j.ibmb.2018.07.001;

Namara LM, Griffin CT, Fitzpatrick D, Kavanagh K, Carolan JC, The effect of entomopathogenic fungal culture filtrate on the immune response and haemolymph proteome of the large pine weevil, Hylobius abietis. Insect Biochem Mol Biol, 101():1-13(2018) [pubmed]

curator keyword: Biological

submitter keyword: proteomics,entomopathogenic fungi, LFQ, pine weevil, immune response

James Carolan
contact affiliation	Environmental Proteomics Lab, Department of Biology, MAynooth University, Ireland.
contact email	james.carolan@mu.ie
lab head
James Carolan
contact affiliation	Biology
contact email	james.carolan@nuim.ie
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD008232
     1. Label: PRIDE project
     2. Name: The effect of entomopathogenic fungal culture filtrate on the immune response and haemolymph proteome of the large pine weevil, Hylobius abietis.