PXD008228

PXD008228 is an original dataset announced via ProteomeXchange.

Title	Proteomic approach for the analysis response of macrophages to Borrelia burgdorferi
Description	Macrophages are cells of the innate immune system with the ability to phagocytose and induce a global pattern of responses that depend on several signalling pathways. In this work we tried to uncover the biosignature of murine bone marrow-derived macrophages and human blood monocytes upon Borrelia infection using transcriptomics and proteomics approaches.
HostingRepository	PRIDE
AnnounceDate	2018-10-22
AnnouncementXML	Submission_2018-10-22_10:10:29.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Mikel Azkargorta
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; scientific name: Borrelia sp. BC7; NCBI TaxID: 1867057;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2017-11-17 02:07:56	ID requested
⏵ 1	2018-10-22 10:10:30	announced

Carreras-Gonz, á, lez A, Navasa N, Mart, í, n-Ruiz I, Lav, í, n JL, Azkargorta M, Atondo E, Barriales D, Mac, í, as-C, á, mara N, Pascual-Itoiz MA, Sampedro L, Tom, á, s-Cort, á, zar J, Pe, ñ, a-Cearra A, Pell, ó, n A, Prados-Rosales R, Abecia L, Elortza F, Aransay AM, Rodr, í, guez H, Anguita J, A multi-omic analysis reveals the regulatory role of CD180 during the response of macrophages to Borrelia burgdorferi. Emerg Microbes Infect, 7(1):19(2018) [pubmed]

curator keyword: Biological

submitter keyword: Borrelia, macrophages, LC-MS/MS

Felix Elortza
contact affiliation	Proteomics Service, CIC bioGUNE, Zamudio, Spain
contact email	felortza@cicbiogune.es
lab head
Mikel Azkargorta
contact affiliation	Proteomics Platform CIC bioGUNE
contact email	mazkargorta@cicbiogune.es
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/10/PXD008228

PRIDE project URI

• PRIDE
  1. PXD008228
     1. Label: PRIDE project
     2. Name: Proteomic approach for the analysis response of macrophages to Borrelia burgdorferi