PXD008141

PXD008141 is an original dataset announced via ProteomeXchange.

Title	Blood plasma and serum samples of healthy donors fractionated on different chromatography sorbents
Description	Blood as connective tissue potentially contain evidence of all processes occurring within the organism, at least in trace amounts. Because of their small size, peptides overcome cell membranes and epithelial barriers more freely than proteins. Among the peptides found in blood, there are both fragments of proteins secreted by various tissues and performing their function in plasma, as well as receptor ligands: hormones, cytokines, mediators of the cellular response. In addition, in minor amounts, there are disease peptide markers (for example, oncomarkers) and even foreign peptides related to pathogenic organisms and infection agents. To characterize the normal peptidome LC-MS/MS analysis was carried out of blood serum and plasma samples taken from 20 healthy donors on TripleTOF 5600+ mass-spectrometer. Sample preparation was carried out based on our previously developed method of peptide desorption from the surface of abundant blood plasma proteins followed by standard chromatographic steps.
HostingRepository	PRIDE
AnnounceDate	2017-11-16
AnnouncementXML	Submission_2018-06-15_07:00:46.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD008141
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Georgij Arapidi
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	Ammonia-loss; Dehydrated; Acetyl
Instrument	TripleTOF 5600

Revision	Datetime	Status	ChangeLog Entry
0	2017-11-06 05:57:53	ID requested
1	2017-11-14 00:36:09	announced
2	2017-11-16 07:06:53	announced	Updated project metadata.
⏵ 3	2018-06-15 07:00:47	announced	Updated project metadata.

Arapidi G, Osetrova M, Ivanova O, Butenko I, Saveleva T, Pavlovich P, Anikanov N, Ivanov V, Govorun V, Peptidomics dataset: Blood plasma and serum samples of healthy donors fractionated on a set of chromatography sorbents. Data Brief, 18():1204-1211(2018) [pubmed]

curator keyword: Biomedical

submitter keyword: Healthy donors, blood plasma and serum, peptidomics, mass-spectrometry, norm

Georgij Pavlovich Arapidi
contact affiliation	Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences
contact email	arapidi@gmail.com
lab head
Georgij Arapidi
contact affiliation	IBCH RAS
contact email	arapidi@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/11/PXD008141

PRIDE project URI

• PRIDE
  1. PXD008141
     1. Label: PRIDE project
     2. Name: Blood plasma and serum samples of healthy donors fractionated on different chromatography sorbents