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PXD008104

PXD008104 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleSecretomes of Cancer-Associated Myofibroblasts and Normal Tissue Myofibroblasts in hypoxia and normoxia C4PR_LIV
DescriptionCancer-associated fibroblasts are a major component of the cancer stroma. Here we focus on gastric cancer associated myofibroblasts (CAMs). CAMs secrete factors that increase the migration, invasion and proliferation of cancer cells when compared to adjacent tissue myofibroblasts (ATMs), or normal tissue myofibroblasts (NTMs). In this study we identified and quantified the proteins secreted by normoxic (21% O2) and hypoxic (1% O2) myofibroblast cells.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_04:41:34.572.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAndrew Jarnuczak
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02017-11-01 11:17:31ID requested
12019-03-04 05:37:21announced
22024-10-22 04:41:42announced2024-10-22: Updated project metadata.
Publication List
10.3390/cancers11020263;
Najgebauer H, Jarnuczak AF, Varro A, Sanderson CM, Integrative Omic Profiling Reveals Unique Hypoxia Induced Signatures in Gastric Cancer Associated Myofibroblasts. Cancers (Basel), 11(2):(2019) [pubmed]
Keyword List
curator keyword: Biological, Biomedical
submitter keyword: gastric cancer,tumour microenvironment,protein secretion
Contact List
Prof Chris Sanderson
contact affiliationDepartment of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Crown Street, Liverpool, L69 3BX, UK
contact emailc.sanderson@liverpool.ac.uk
lab head
Andrew Jarnuczak
contact affiliationEBI
contact emailandrew.at.astra@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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