PXD008104

PXD008104 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Secretomes of Cancer-Associated Myofibroblasts and Normal Tissue Myofibroblasts in hypoxia and normoxia C4PR_LIV
Description	Cancer-associated fibroblasts are a major component of the cancer stroma. Here we focus on gastric cancer associated myofibroblasts (CAMs). CAMs secrete factors that increase the migration, invasion and proliferation of cancer cells when compared to adjacent tissue myofibroblasts (ATMs), or normal tissue myofibroblasts (NTMs). In this study we identified and quantified the proteins secreted by normoxic (21% O2) and hypoxic (1% O2) myofibroblast cells.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:41:34.572.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Andrew Jarnuczak
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2017-11-01 11:17:31	ID requested
1	2019-03-04 05:37:21	announced
⏵ 2	2024-10-22 04:41:42	announced	2024-10-22: Updated project metadata.

Publication List

10.3390/cancers11020263;
Najgebauer H, Jarnuczak AF, Varro A, Sanderson CM, Integrative Omic Profiling Reveals Unique Hypoxia Induced Signatures in Gastric Cancer Associated Myofibroblasts. Cancers (Basel), 11(2):(2019) [pubmed]

10.3390/cancers11020263;

Najgebauer H, Jarnuczak AF, Varro A, Sanderson CM, Integrative Omic Profiling Reveals Unique Hypoxia Induced Signatures in Gastric Cancer Associated Myofibroblasts. Cancers (Basel), 11(2):(2019) [pubmed]

Keyword List

curator keyword: Biological, Biomedical
submitter keyword: gastric cancer,tumour microenvironment,protein secretion

curator keyword: Biological, Biomedical

submitter keyword: gastric cancer,tumour microenvironment,protein secretion

Contact List

Prof Chris Sanderson
contact affiliation	Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Crown Street, Liverpool, L69 3BX, UK
contact email	c.sanderson@liverpool.ac.uk
lab head
Andrew Jarnuczak
contact affiliation	EBI
contact email	andrew.at.astra@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/03/PXD008104
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/03/PXD008104

PRIDE project URI

Repository Record List

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