PXD008104 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Secretomes of Cancer-Associated Myofibroblasts and Normal Tissue Myofibroblasts in hypoxia and normoxia C4PR_LIV |
Description | Cancer-associated fibroblasts are a major component of the cancer stroma. Here we focus on gastric cancer associated myofibroblasts (CAMs). CAMs secrete factors that increase the migration, invasion and proliferation of cancer cells when compared to adjacent tissue myofibroblasts (ATMs), or normal tissue myofibroblasts (NTMs). In this study we identified and quantified the proteins secreted by normoxic (21% O2) and hypoxic (1% O2) myofibroblast cells. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_04:41:34.572.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Andrew Jarnuczak |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2017-11-01 11:17:31 | ID requested | |
1 | 2019-03-04 05:37:21 | announced | |
⏵ 2 | 2024-10-22 04:41:42 | announced | 2024-10-22: Updated project metadata. |
Publication List
10.3390/cancers11020263; |
Najgebauer H, Jarnuczak AF, Varro A, Sanderson CM, Integrative Omic Profiling Reveals Unique Hypoxia Induced Signatures in Gastric Cancer Associated Myofibroblasts. Cancers (Basel), 11(2):(2019) [pubmed] |
Keyword List
curator keyword: Biological, Biomedical |
submitter keyword: gastric cancer,tumour microenvironment,protein secretion |
Contact List
Prof Chris Sanderson |
contact affiliation | Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Crown Street, Liverpool, L69 3BX, UK |
contact email | c.sanderson@liverpool.ac.uk |
lab head | |
Andrew Jarnuczak |
contact affiliation | EBI |
contact email | andrew.at.astra@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/03/PXD008104 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD008104
- Label: PRIDE project
- Name: Secretomes of Cancer-Associated Myofibroblasts and Normal Tissue Myofibroblasts in hypoxia and normoxia C4PR_LIV