PXD008092

PXD008092 is an original dataset announced via ProteomeXchange.

Title	Moving Forward Real-Time Proteomics Mass Spectrometry by Remote Infrared Matrix-Assisted Laser Desorption-Ionization
Description	Novel development makes remote real-time analysis with possible translation to in-vivo a reality. Remote Infrared Matrix Assisted Laser Desorption Ionization (Remote IR MALDI) system with endogenous water as matrix becomes real and allows to envisage real-time proteomics to be performed in the in-vivo context. Remote IR MALDI is demonstrated to be used to analyze peptides and proteins. Very interestingly, the corresponding mass spectra show ESI like charge states distribution, opening many applications for structural elucidation to be performed in real-time by Top-Down analysis. The charge states show no dependence toward laser wavelength or length of the transfer tube allowing for remote analyses to be perform 5 m away from the mass spectrometry (MS) instrument without modification of spectra. This brings also interesting features to the understanding of IR MALDI ionization mechanism
HostingRepository	PRIDE
AnnounceDate	2018-04-20
AnnouncementXML	Submission_2018-04-20_01:48:19.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Fournier Isabelle
SpeciesList	scientific name: Bos taurus (Bovine); NCBI TaxID: 9913; scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Synapt MS

Revision	Datetime	Status	ChangeLog Entry
0	2017-11-01 02:06:19	ID requested
⏵ 1	2018-04-20 01:48:21	announced

Fatou B, Ziskind M, Saudemont P, Quanico J, Focsa C, Salzet M, Fournier I, Remote Atmospheric Pressure Infrared Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry (Remote IR-MALDI MS) of Proteins. Mol Cell Proteomics, 17(8):1637-1649(2018) [pubmed]

Fatou B, Saudemont P, Leblanc E, Vinatier D, Mesdag V, Wisztorski M, Focsa C, Salzet M, Ziskind M, Fournier I, In vivo Real-Time Mass Spectrometry for Guided Surgery Application. Sci Rep, 6():25919(2016) [pubmed]

curator keyword: Technical

submitter keyword: Mass Spectrometry • Real-Time Analysis • Remote IR MALDI• Proteins • Charge State Distribution

Michel Salzet
contact affiliation	University of Lille, INSERM U1192 - Laboratoire Protéomique, Réponse Inflammatoire et Spectrométrie de Masse (PRISM), F-59000 Lille, France.
contact email	michel.salzet@univ-lille1.fr
lab head
Fournier Isabelle
contact affiliation	University of Lille
contact email	isabelle.fournier@univ-lille1.fr
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/04/PXD008092

PRIDE project URI

• PRIDE
  1. PXD008092
     1. Label: PRIDE project
     2. Name: Moving Forward Real-Time Proteomics Mass Spectrometry by Remote Infrared Matrix-Assisted Laser Desorption-Ionization