PXD007995

PXD007995 is an original dataset announced via ProteomeXchange.

Title	Quantifying extracellular matrix turnover in human lung scaffold cultures
Description	Tissue engeneering using biological scaffolds are a promising technique for solving the shortage of donor organs for patients suffering of end stage organ faliure. We introduced stable isotope labeling with amino acids in a tissue culture setting, which enabeled us to distinguish between the biological scaffold and the proteome of the reppulating cells. Our study gives new insight into ECM turnover in repopulating lung scaffolds and the technique will be a valuble tool for future studies of cell-ECM interaction in tissue engeneering.
HostingRepository	PRIDE
AnnounceDate	2018-04-09
AnnouncementXML	Submission_2018-04-09_01:12:27.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Oskar Rosmark
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2017-10-18 07:04:25	ID requested
⏵ 1	2018-04-09 01:12:28	announced

Rosmark O, Å, hrman E, M, ü, ller C, Elowsson Rendin L, Eriksson L, Malmstr, ö, m A, Hallgren O, Larsson-Callerfelt AK, Westergren-Thorsson G, Malmstr, ö, m J, Quantifying extracellular matrix turnover in human lung scaffold cultures. Sci Rep, 8(1):5409(2018) [pubmed]

curator keyword: Biological, Biomedical

submitter keyword: Human, lung, SILAC, ECM

Gunilla Westergren-Thorsson
contact affiliation	Lung Biology, Department of Experimental Medical Science, Lund University, Sweden
contact email	gunilla.westergren-thorsson@med.lu.se
lab head
Oskar Rosmark
contact affiliation	Lund University
contact email	oskar.rosmark@med.lu.se
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/04/PXD007995

PRIDE project URI

• PRIDE
  1. PXD007995
     1. Label: PRIDE project
     2. Name: Quantifying extracellular matrix turnover in human lung scaffold cultures