PXD007944

PXD007944 is an original dataset announced via ProteomeXchange.

Title	Hydroxyapatite-binding plasma proteins in Age-related macular degenaration
Description	This project identifies and quantitates Hydroxyapatite binding proteins (HAP) in plasma genotyped for complement factor H (CFH) polymorphism in late stage age-related macular degeneration (AMD) patients by sequential window acquisition of all theoretical mass spectra (SWATH). This study provides insights into factors contributing to the formation of sub-retinal pigment epithelial (RPE) deposits and explores the effect of AMD-associated CFH polymorphism on deposit composition.
HostingRepository	PRIDE
AnnounceDate	2018-03-28
AnnouncementXML	Submission_2018-03-28_03:01:12.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Silvia Synowsky
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	TripleTOF 5600

Revision	Datetime	Status	ChangeLog Entry
0	2017-10-11 04:06:26	ID requested
⏵ 1	2018-03-28 03:01:13	announced

Arya S, Emri E, Synowsky SA, Shirran SL, Barzegar-Befroei N, Peto T, Botting CH, Lengyel I, Stewart AJ, Quantitative analysis of hydroxyapatite-binding plasma proteins in genotyped individuals with late-stage age-related macular degeneration. Exp Eye Res, 172():21-29(2018) [pubmed]

curator keyword: Biological, Biomedical

submitter keyword: Sub-retinal pigment epithelial deposits, AMD, Human plasma, hydroxyapatite-binding

Alan J. Stewart
contact affiliation	School of Medicine, University of St Andrews, St Andrews, KY16 9TF, UK
contact email	ajs21@st-andrews.ac.uk
lab head
Silvia Synowsky
contact affiliation	University of St Andrews
contact email	sas28@st-andrews.ac.uk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/03/PXD007944

PRIDE project URI

• PRIDE
  1. PXD007944
     1. Label: PRIDE project
     2. Name: Hydroxyapatite-binding plasma proteins in Age-related macular degenaration