PXD007926

PXD007926 is an original dataset announced via ProteomeXchange.

Title	High Field Asymmetric Waveform Ion Mobility Spectrometry in Non-targeted Bottom-up Proteomics of Dried Blood Spot
Description	Dried Blood Spots samples are a rich source of proteins and have therefore great potential for proteomics biomarker discovery studies. Only a few articles have used DBS samples for non-targeted bottom-up protein analysis, probably due to the complexity of the DBS samples. Gas-phase separation by ion mobility spectrometry such as Field Asymmetric Waveform Ion Mobility (FAIMS) could be useful in analysis of DBS samples as FAIMS has previously shown to be advantageous for bottom-up protein analysis of complex samples. The aim of this project was therefore to evaluate FAIMS in non-targeted analysis of Dried Blood Spots.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:14:49.984.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Cecilie Rosting
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue
Instrument	LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2017-10-09 05:34:56	ID requested
1	2018-05-03 07:21:58	announced
⏵ 2	2024-10-22 04:14:58	announced	2024-10-22: Updated project metadata.

10.1021/acs.jproteome.7b00746;

Rosting C, Yu J, Cooper HJ, High Field Asymmetric Waveform Ion Mobility Spectrometry in Nontargeted Bottom-up Proteomics of Dried Blood Spots. J Proteome Res, 17(6):1997-2004(2018) [pubmed]

curator keyword: Technical, Biomedical

submitter keyword: FAIMS,Dried Blood Spot, Non-targeted, bottom-up, Proteomics

Helen J Cooper
contact affiliation	Scool of Bioscience, University of Birmingham, Edgbaston Birmingham B15 2TT United Kingdom
contact email	h.j.cooper@bham.ac.uk
lab head
Cecilie Rosting
contact affiliation	University of Oslo
contact email	cecilie.rosting@farmasi.uio.no
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/05/PXD007926

PRIDE project URI

• PRIDE
  1. PXD007926
     1. Label: PRIDE project
     2. Name: High Field Asymmetric Waveform Ion Mobility Spectrometry in Non-targeted Bottom-up Proteomics of Dried Blood Spot