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PXD007898

PXD007898 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleFibroblast activation
DescriptionThe tumour secretome contains proteinaceous factors that could potentially cause activation of neighbouring fibroblasts via contact-independent processes. In this project, we aim to identify such paracrine activators of tumour origin and elucidate the functional impact of activation on fibroblasts and the tumour metastatic process.
HostingRepositoryPRIDE
AnnounceDate2018-07-23
AnnouncementXMLSubmission_2018-07-23_09:14:29.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterwei wu
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListphosphorylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02017-10-03 07:53:43ID requested
12018-07-23 09:14:30announced
Publication List
Wu W, Zaal EA, Berkers CR, Lemeer S, Heck AJR, CTGF/VEGFA-activated Fibroblasts Promote Tumor Migration Through Micro-environmental Modulation. Mol Cell Proteomics, 17(8):1502-1514(2018) [pubmed]
Keyword List
curator keyword: Biomedical
submitter keyword: Tumor microenvironment
fibroblast activation
reciprocal signaling
secretome
mass spectrometry.
Contact List
Albert JR Heck
contact affiliationBiomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, 3584 CH Utrecht, the Netherlands. Netherlands Proteomics Centre, Padualaan 8, 3584 CH Utrecht, the Netherlands.
contact emaila.j.r.heck@uu.nl
lab head
wei wu
contact affiliationUtrecht University
contact emailw.wu1@uu.nl
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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