PXD007843

PXD007843 is an original dataset announced via ProteomeXchange.

Title	Hypoxia induces Foxn1 and Mmp-9 expression in keratinocytes: proteomics analysis of mouse keratinocytes transiently activated by Foxn1
Description	Recent studies have shown that transcription factor Foxn1 expressed in keratinocytes is involved in skin wound healing process, yet how Foxn1 functions remains largely unknown. Proteomic analysis using a two-dimensional differential gel electrophoresis (2D-DIGE) technique coupled with MALDI-TOF/TOF was used to analyze in vitro cultured keratinocytes transfected with adenoviral vector carrying Foxn1-GFP or GFP-alone (control). Sixty-six of sixty-nine protein spots differed in abundance between compared groups were identified.
HostingRepository	PRIDE
AnnounceDate	2018-04-09
AnnouncementXML	Submission_2018-04-09_00:43:32.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Mariola Dietrich
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	iodoacetamide derivatized residue
Instrument	autoflex

Revision	Datetime	Status	ChangeLog Entry
0	2017-09-26 02:26:14	ID requested
⏵ 1	2018-04-09 00:43:33	announced

Kur-Piotrowska A, Bukowska J, Kopcewicz MM, Dietrich M, Nynca J, Slowinska M, Gawronska-Kozak B, Foxn1 expression in keratinocytes is stimulated by hypoxia: further evidence of its role in skin wound healing. Sci Rep, 8(1):5425(2018) [pubmed]

curator keyword: Biological, Biomedical

submitter keyword: Foxn1, Mmp-9, skin, wound healing, hypoxia, proteomics

Mariola Dietrich
contact affiliation	Institute of Animal Reproduction and Food Research of Polish Academy of Sciences
contact email	m.dietrich@pan.olsztyn.pl
lab head
Mariola Dietrich
contact affiliation	Polish Academy of Sciences
contact email	m.dietrich@pan.olsztyn.pl
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/04/PXD007843

PRIDE project URI

• PRIDE
  1. PXD007843
     1. Label: PRIDE project
     2. Name: Hypoxia induces Foxn1 and Mmp-9 expression in keratinocytes: proteomics analysis of mouse keratinocytes transiently activated by Foxn1