PXD007841

PXD007841 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Comparative analysis of mRNA degradation and protein degradation in 68 pairs of adjacent prostate tissue samples indicates high stability of proteins
Description	Here we investigated the degradation of mRNA and protein in 68 pairs of adjacent prostate tissue samples using RNA-seq and pressure cycling technology (PCT) coupled with SWATH mass spectrometry and developed a score, the Proteome Integrity Number (PIN), to quantify the extent of protein degradation in the samples.
HostingRepository	PRIDE
AnnounceDate	2019-06-13
AnnouncementXML	Submission_2019-06-12_17:39:18.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Wenguang Shao
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	TripleTOF 5600

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2017-09-26 01:52:09	ID requested
⏵ 1	2019-06-12 17:39:19	announced

Publication List

Shao W, Guo T, Toussaint NC, Xue P, Wagner U, Li L, Charmpi K, Zhu Y, Wu J, Buljan M, Sun R, Rutishauser D, Hermanns T, Fankhauser CD, Poyet C, Ljubicic J, Rupp N, R, ü, schoff JH, Zhong Q, Beyer A, Ji J, Collins BC, Liu Y, R, ä, tsch G, Wild PJ, Aebersold R, Comparative analysis of mRNA and protein degradation in prostate tissues indicates high stability of proteins. Nat Commun, 10(1):2524(2019) [pubmed]

Shao W, Guo T, Toussaint NC, Xue P, Wagner U, Li L, Charmpi K, Zhu Y, Wu J, Buljan M, Sun R, Rutishauser D, Hermanns T, Fankhauser CD, Poyet C, Ljubicic J, Rupp N, R, ü, schoff JH, Zhong Q, Beyer A, Ji J, Collins BC, Liu Y, R, ä, tsch G, Wild PJ, Aebersold R, Comparative analysis of mRNA and protein degradation in prostate tissues indicates high stability of proteins. Nat Commun, 10(1):2524(2019) [pubmed]

Keyword List

curator keyword: Biomedical
submitter keyword: DIA/SWATH
clinical tissues
protein stability

curator keyword: Biomedical

submitter keyword: DIA/SWATH

clinical tissues

protein stability

Contact List

Ruedi Aebersold
contact affiliation	Department of Biology, Institute of Molecular Systems Biology, ETH, Zurich, Switzerland
contact email	aebersold@imsb.biol.ethz.ch
lab head
Wenguang Shao
contact affiliation	ETH Zurich
contact email	shaowenguang@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/06/PXD007841
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/06/PXD007841

PRIDE project URI

Repository Record List

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