PXD007820

PXD007820 is an original dataset announced via ProteomeXchange.

Title	Proteomic response to the thaxtomin phytotoxin elicitor cellobiose and to the deletion of the cellulose utilization regulator CebR in Streptomyces scabies
Description	Streptomyces scabies is a plant pathogen responsible for common scab disease on root and tuber crops. The transport of the cellulose by-products cellobiose and cellotriose into the cell induces the biosynthesis of the main phytotoxin thaxtomin A. These carbohydrates bind to the cis-acting sequences of the cellulose utilization repressor CebR and thereby induce the expression of the thaxtomin activator TxtR. We performed a shotgun proteomic experiment to compare the wild-type S. scabies 87-22 and its cebR null mutant in the absence or presence of cellobiose. The global intracellular response during virulent behaviour of this plant pathogen could be determined during this experiment.
HostingRepository	PRIDE
AnnounceDate	2018-10-18
AnnouncementXML	Submission_2018-10-18_00:29:20.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sören Planckaert
SpeciesList	scientific name: Streptomyces scabiei 87.22; NCBI TaxID: 680198;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Synapt MS

Revision	Datetime	Status	ChangeLog Entry
0	2017-09-22 08:14:27	ID requested
⏵ 1	2018-10-18 00:29:22	announced

Planckaert S, Jourdan S, Francis IM, Deflandre B, Rigali S, Devreese B, Proteomic Response to Thaxtomin Phytotoxin Elicitor Cellobiose and to Deletion of Cellulose Utilization Regulator CebR in Streptomyces scabies. J Proteome Res, 17(11):3837-3852(2018) [pubmed]

curator keyword: Biological

submitter keyword: Streptomyces scabies, pathogenicity, LC-MSe, Synapt MS

Bart Devreese
contact affiliation	WE-10, L-ProBE, University Ghent, Belgium
contact email	bart.devreese@ugent.be
lab head
Sören Planckaert
contact affiliation	University Ghent, WE10, L-ProBE
contact email	soren.planckaert@ugent.be
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD007820
     1. Label: PRIDE project
     2. Name: Proteomic response to the thaxtomin phytotoxin elicitor cellobiose and to the deletion of the cellulose utilization regulator CebR in Streptomyces scabies