PXD007766

PXD007766 is an original dataset announced via ProteomeXchange.

Title	Proteomic characterisation of bovine and avian purified protein derivatives and identification of specific antigens for serodiagnosis of bovine tuberculosis
Description	Bovine purified protein derivative (bPPD) and avian purified protein derivative (aPPD) arewidely used forbovine tuberculosis diagnosis. However, little is known about their qualitative and quantitative characteristics, which makes their standardisation difficult. In addition, bPPDcan give false-positive tuberculosis results because of sequence homologybetween Mycobacterium bovis andM. avium proteins. Here we used proteomics to characterisebPPD, aPPD and an immunopurifiedsubcomplexfrombPPD called P22.
HostingRepository	PRIDE
AnnounceDate	2018-11-22
AnnouncementXML	Submission_2018-11-22_01:54:51.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD007766
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Sergio Ciordia
SpeciesList	scientific name: Mycobacterium avium subsp. avium ATCC 25291; NCBI TaxID: 553481; scientific name: Mycobacterium bovis AN5; NCBI TaxID: 1389959;
ModificationList	Methylthio; Glu->pyro-Glu; Oxidation; Acetyl; Gln->pyro-Glu
Instrument	TripleTOF 5600

Revision	Datetime	Status	ChangeLog Entry
0	2017-09-18 03:27:16	ID requested
⏵ 1	2018-11-22 01:54:52	announced

Infantes-Lorenzo JA, Moreno I, Risalde ML Á, Roy Á, Villar M, Romero B, Ibarrola N, de la Fuente J, Puentes E, de Juan L, Gort, á, zar C, Bezos J, Dom, í, nguez L, Dom, í, nguez M, Proteomic characterisation of bovine and avian purified protein derivatives and identification of specific antigens for serodiagnosis of bovine tuberculosis. Clin Proteomics, 14():36(2017) [pubmed]

curator keyword: Biological

submitter keyword: tuberculosis, PPD, proteome, cross-reaction

Mercedes Domínguez
contact affiliation	Instituto de Salud Carlos III- Departamento de Inmunología Microbiana e Inmunogenética
contact email	mdominguez@isciii.es
lab head
Sergio Ciordia
contact affiliation	National Center for Biotechnology
contact email	sciordia@cnb.csic.es
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/11/PXD007766

PRIDE project URI

• PRIDE
  1. PXD007766
     1. Label: PRIDE project
     2. Name: Proteomic characterisation of bovine and avian purified protein derivatives and identification of specific antigens for serodiagnosis of bovine tuberculosis