PXD007755

PXD007755 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteomic profiling of rhabdomyosarcoma-derived exosomes yield functional role for extracellular vesicles
Description	In this study, we interrogated the protein composition of exosomes purified from cell culture supernatants of 5 different RMS cell lines, by LC-MS/MS technology and analysis using bio-informatics tools. We attempted to characterize the differences and similarities between exosomes derived from ERMS and ARMS cells, and common as well as unique characteristics of RMS exosome protein content when compared to that of other cancer and non-cancer cells. Our results identify potential protein exosome biomarkers for RMS to be further investigated in future clinical studies.
HostingRepository	PRIDE
AnnounceDate	2019-08-29
AnnouncementXML	Submission_2019-08-29_06:01:09.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jingfu Zhao
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Velos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2017-09-18 01:40:31	ID requested
⏵ 1	2019-08-29 06:01:10	announced

Publication List

Rammal G, Fahs A, Kobeissy F, Mechref Y, Zhao J, Zhu R, Diab-Assaf M, Saab R, Ghayad SE, Proteomic Profiling of Rhabdomyosarcoma-Derived Exosomes Yield Insights into Their Functional Role in Paracrine Signaling. J Proteome Res, 18(10):3567-3579(2019) [pubmed]

Rammal G, Fahs A, Kobeissy F, Mechref Y, Zhao J, Zhu R, Diab-Assaf M, Saab R, Ghayad SE, Proteomic Profiling of Rhabdomyosarcoma-Derived Exosomes Yield Insights into Their Functional Role in Paracrine Signaling. J Proteome Res, 18(10):3567-3579(2019) [pubmed]

Keyword List

curator keyword: Biomedical
submitter keyword: Rhabdomyosarcoma, exosomes, proteomics, pathways

curator keyword: Biomedical

submitter keyword: Rhabdomyosarcoma, exosomes, proteomics, pathways

Contact List

Yehia S Mechref
contact affiliation	Texas Tech University
contact email	yehia.mechref@ttu.edu
lab head
Jingfu Zhao
contact affiliation	Texas Tech University
contact email	jingfu.zhao@ttu.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/08/PXD007755
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/08/PXD007755

PRIDE project URI

Repository Record List

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