PXD007705

PXD007705 is an original dataset announced via ProteomeXchange.

Title	Comparative proteomics reveals a diagnostic signature for pulmonary head-and-neck cancer metastasis.
Description	This study represents a proteomic resource for HNSCC and SQCLC with quantitative protein expression data for 7800 proteins and provides a proteomic diagnostic signature for classification for undetermined secondary lung tumors in HNSCC patients. By quantitative mass-spectrometry-based proteomics, we characterized a cohort of 63 squamous cell carcinomas of the lung (SQCLC), 49 of the head and neck region (HNSCC) and 51 HNSCC-correlated lung tumors with squamous cell histology that evolved in the course of the disease.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:44:20.724.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Kuan-Ting Pan
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF-X; Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2017-09-11 00:41:04	ID requested
1	2018-08-06 04:14:28	announced
2	2019-03-07 05:45:08	announced	Updated publication reference for PubMed record(s): 30097507.
⏵ 3	2024-10-22 04:44:26	announced	2024-10-22: Updated project metadata.

10.15252/emmm.201708428;

Bohnenberger H, Kaderali L, Str, ö, bel P, Yepes D, Plessmann U, Dharia NV, Yao S, Heydt C, Merkelbach-Bruse S, Emmert A, Hoffmann J, Bodemeyer J, Reuter-Jessen K, Lois AM, Dr, ö, ge LH, Baumeister P, Walz C, Biggemann L, Walter R, H, ä, upl B, Comoglio F, Pan KT, Scheich S, Lenz C, K, ü, ffer S, Bremmer F, Kitz J, Sitte M, Bei, ß, barth T, Hinterthaner M, Sebastian M, Lotz J, Schildhaus HU, Wolff H, Danner BC, Brandts C, B, ü, ttner R, Canis M, Stegmaier K, Serve H, Urlaub H, Oellerich T, metastasis. EMBO Mol Med, 10(9):(2018) [pubmed]

curator keyword: Biomedical

submitter keyword: head and neck cancer, human tissue proteomics, lung cancer, squamous cell carcinoma,diagnostic Biomarker, metastasis

Thomas Oellerich
contact affiliation	Department of Medicine II, Hematology/Oncology, Goethe University, Germany German Cancer Research Center and German Cancer Consortium, Germany
contact email	Thomas.Oellerich@kgu.de
lab head
Kuan-Ting Pan
contact affiliation	MPI for Biophysical Chemistry
contact email	kpan@mpibpc.mpg.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/08/PXD007705

PRIDE project URI

• PRIDE
  1. PXD007705
     1. Label: PRIDE project
     2. Name: Comparative proteomics reveals a diagnostic signature for pulmonary head-and-neck cancer metastasis.