PXD007691

PXD007691 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Quantitative proteomic analysis of polarized RPE secretome
Description	To investigate the impact of serine protease HtrA1 on the polarized RPE secretome.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:40:12.890.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Chia-yi Chen
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	dimethylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2017-09-07 06:32:27	ID requested
1	2018-04-09 01:40:49	announced
⏵ 2	2024-10-22 04:40:18	announced	2024-10-22: Updated project metadata.

Publication List

10.1016/j.matbio.2018.03.013;
Chen CY, Melo E, Jakob P, Friedlein A, Els, ä, sser B, Goettig P, Kueppers V, Delobel F, Stucki C, Dunkley T, Fauser S, Schilling O, Iacone R, N-Terminomics identifies HtrA1 cleavage of thrombospondin-1 with generation of a proangiogenic fragment in the polarized retinal pigment epithelial cell model of age-related macular degeneration. Matrix Biol, 70():84-101(2018) [pubmed]

10.1016/j.matbio.2018.03.013;

Chen CY, Melo E, Jakob P, Friedlein A, Els, ä, sser B, Goettig P, Kueppers V, Delobel F, Stucki C, Dunkley T, Fauser S, Schilling O, Iacone R, N-Terminomics identifies HtrA1 cleavage of thrombospondin-1 with generation of a proangiogenic fragment in the polarized retinal pigment epithelial cell model of age-related macular degeneration. Matrix Biol, 70():84-101(2018) [pubmed]

Keyword List

curator keyword: Biological, Biomedical
submitter keyword: RPE, Age-related Macular Degeneration, HtrA1, secretome

curator keyword: Biological, Biomedical

submitter keyword: RPE, Age-related Macular Degeneration, HtrA1, secretome

Contact List

Oliver Schilling
contact affiliation	Institute of Molecular Medicine and Cell Research, University Freiburg
contact email	oilver.schilling@mol-med.uni-freiburg.de
lab head
Chia-yi Chen
contact affiliation	Institute of Molecular Medicine and Cell Research, University Freiburg
contact email	chia-yi.chen@mol-med.uni-freiburg.de
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/04/PXD007691
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/04/PXD007691

PRIDE project URI

Repository Record List

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